Results 171 to 180 of about 5,628,095 (258)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Triphasic clinical course of driveline exit-site inflammation managed outpatient via photographic monitoring: An allied health case report of two left ventricular assist device patients. [PDF]

JHLT Open
Taketani S, Saito S, Matsuura R, Sueyoshi A, Kubota K, Handa K, Miyagawa S.   +6 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Ignacio Arellano, Christoph Strosetzki, Edwin Williamson (eds.), Autoridad y poder en el Siglo de Oro, Madrid, Frankfurt, Vervuert-Iberoamericana, 2009, 293 p.

Nuevo mundo - Mundos Nuevos, 2010
Aude Argouse
doaj   +1 more source

Collective interests, health research ethics and data governance for Indigenous Sámi populations. [PDF]

PLoS Med
Siri SRA, Mienna CS, Axelsson P.
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Enrique Villalba y Emilio Torné, El nervio de la república. El oficio de escribano en el siglo de Oro, Madrid, Calambur, 2010, 445 p., colección Biblioteca Litterae 24.

Nuevo mundo - Mundos Nuevos, 2013
Aude Argouse
doaj   +1 more source

Allergic bronchopulmonary mycosis caused by <i>Schizophyllum commune</i> in a patient with severe food allergy and asthma. [PDF]

IDCases
Ohkoshi Y, Murabayashi H, Sakai K, Onodera H, Takakuwa Y, Hashimoto M, Watanabe A, Yokota SI.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Antonio Castillo Gómez, Leggere nella Spagna moderna. Erudizione, religiosità e svago, Bolonia, Pàtron Editore, 2013, 126 p.

Nuevo mundo - Mundos Nuevos, 2013
Carlos Alberto González Sánchez
doaj   +1 more source