Results 51 to 60 of about 583,690 (214)

Can words be read without abstract letter identities?

open access: yesFrontiers in Psychology, 2014
Most theories of reading and writing posit a level of representation that codes abstract letter identities (ALIs) independent of the font, case, and even modality in which the letter was presented or produced (e.g., Caramazza & Hillis, 1990).
Simon Fischer-Baum
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Début de l’écriture en situation de bilinguisme créole/français

open access: yesÉtudes Créoles, 2017
The interests that the analysis of children’s texts present are quite numerous. If we focalise on bilingualism, we should understand and question the strategies that children use and the difficulties they encounter.
Bien-Aimé Guerlande
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Corpus of Young Learners’ English in the Baltic Region – Texts for Studies on Sustainable Development

open access: yesDiscourse and Communication for Sustainable Education, 2016
In order to reach far in the work for sustainable development, communication in foreign languages prior to strategic decisions is required from international partners. In this communication English has become the lingua franca. Even though the use of EFL
Sundh Stellan
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Assessment tasks for a written test: an analysis from student’s written production

open access: yesRevista Brasileira de Ensino de Ciência e Tecnologia, 2019
This paper aims to present a discussion about the potential of tasks in a written test as resources for an assessment as an investigation practice in which, from the analysis of written production of students, the teacher goes beyond checking for a ...
Fernando Francisco Pereira   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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