Results 11 to 20 of about 15,148 (241)

Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Côte d'Ivoire. [PDF]

PLoS Negl Trop Dis, 2019
Background A single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Edi C, Bjerum CM, Ouattara AF, Chhonker YS, Penali LK, Méité A, Koudou BG, Weil GJ, King CL, Murry DJ.   +9 more
europepmc   +8 more sources

Assessing the presence of Wuchereria bancrofti in vector and human populations from urban communities in Conakry, Guinea [PDF]

Parasites & Vectors, 2015
The Global Programme to Eliminate Lymphatic Filariasis was launched in 2000 with the goal of interrupting transmission of lymphatic filariasis (LF) through multiple rounds of mass drug administration (MDA).
Bernard L. Kouassi, Dziedzom K. de Souza, André Goepogui, Charles A. Narh, Sandra A. King, Baldé S. Mamadou, Lamia Diakité, Samuel Dadzie, Daniel A. Boakye, Jürg Utzinger, Moses J. Bockarie, Benjamin G. Koudou   +11 more
semanticscholar   +8 more sources

Mapping of lymphatic filariasis in loiasis areas: A new strategy shows no evidence for Wuchereria bancrofti endemicity in Cameroon. [PDF]

PLoS Negl Trop Dis, 2019
Background Mapping of lymphatic filariasis (LF) caused by Wuchereria bancrofti largely relies on the detection of circulating antigen using ICT cards. Several studies have recently shown that this test can be cross-reactive with sera of subjects heavily ...
Wanji S, Esum ME, Njouendou AJ, Mbeng AA, Chounna Ndongmo PW, Abong RA, Fru J, Fombad FF, Nchanji GT, Ngongeh G, Ngandjui NV, Enyong PI, Storey H, Curtis KC, Fischer K, Fauver JR, Lew D, Goss CW, Fischer PU.   +18 more
europepmc   +5 more sources

Selection and exploitation of prevalent, tandemly repeated genomic targets for improved real-time PCR-based detection of Wuchereria bancrofti and Plasmodium falciparum in mosquitoes. [PDF]

PLoS One, 2020
Background Optimization of polymerase chain reaction (PCR)-based diagnostics requires the careful selection of molecular targets that are both highly repetitive and pathogen-specific.
Zulch MF, Pilotte N, Grant JR, Minetti C, Reimer LJ, Williams SA.   +5 more
europepmc   +2 more sources

Wuchereria bancrofti infection is linked to systemic activation of CD4 and CD8 T cells. [PDF]

PLoS Negl Trop Dis, 2019
Background Susceptibility to HIV has been linked to systemic CD4+ T cell activation in cohorts of seronegative individuals with high HIV-exposure risk.
Kroidl I, Chachage M, Mnkai J, Nsojo A, Berninghoff M, Verweij JJ, Maganga L, Ntinginya NE, Maboko L, Clowes P, Hoelscher M, Saathoff E, Geldmacher C.   +12 more
europepmc   +2 more sources

Wuchereria bancrofti: Unusual Presentation as Pancytopenia [PDF]

Journal of Clinical and Diagnostic Research, 2016
Wuchereria bancrofti is an endemic filarial nematode spread by a mosquito vector. The clinical manifestations vary from asymptomatic microfilaremeia to lymhoedema.
Mili Jain, Ayush Shukla, Ashutosh Kumar, Rashmi Kushwaha, Uma Shankar Singh   +4 more
doaj   +2 more sources

Assessing the Presence of Wuchereria bancrofti Infections in Vectors Using Xenomonitoring in Lymphatic Filariasis Endemic Districts in Ghana. [PDF]

Trop Med Infect Dis, 2019
Mass drug administration (MDA) is the current mainstay to interrupt the transmission of lymphatic filariasis. To monitor whether MDA is effective and transmission of lymphatic filariasis indeed has been interrupted, rigorous surveillance is required ...
Pi-Bansa S, Osei JHN, Kartey-Attipoe WD, Elhassan E, Agyemang D, Otoo S, Dadzie SK, Appawu MA, Wilson MD, Koudou BG, de Souza DK, Utzinger J, Boakye DA.   +12 more
europepmc   +2 more sources

Multiple filarial species microfilaraemia: a comparative study of areas with endemic and sporadic onchocerciasis [PDF]

Journal of Vector Borne Diseases, 2011
Background & objectives: The study was aimed at determining the pattern of co-occurrence of species ofmicrofilaraemia between onchocerciasis endemic and sporadic populations.Methods: From every consenting person of one year and above, 50 μl of day and ...
Emmanuel Uttah & Dominic C. Ibeh
doaj   +2 more sources

Expression, purification, and inhibition profile of dihydrofolate reductase from the filarial nematode Wuchereria bancrofti. [PDF]

PLoS One, 2018
Filariasis is a tropical disease caused by the parasitic nematodes Wuchereria bancrofti and Brugia malayi. Known inhibitors of dihydrofolate reductase (DHFR) have been previously shown to kill Brugia malayi nematodes and to inhibit Brugia malayi DHFR ...
Tobias AM, Toska D, Lange K, Eck T, Bhat R, Janson CA, Rotella DP, Gubler U, Goodey NM.   +8 more
europepmc   +2 more sources

Further evidence of the cross-reactivity of the Binax NOW® Filariasis ICT cards to non-Wuchereria bancrofti filariae: experimental studies with Loa loa and Onchocerca ochengi [PDF]

Parasites & Vectors, 2016
BackgroundThe immunochromatographic test (ICT) for lymphatic filariasis is a serological test designed for unequivocal detection of circulating Wuchereria bancrofti antigen.
S. Wanji, Nathalie Amvongo-Adjia, A. Njouendou, Jonas A Kengne-Ouafo, Winston Patrick Chounna Ndongmo, Fanny F. Fombad, B. Koudou, P. Enyong, M. Bockarie   +8 more
semanticscholar   +5 more sources