Results 41 to 50 of about 5,549 (219)

Interactions between sleep, inflammation, immunity and infections: A narrative review

Immunity, Inflammation and Disease, Volume 12, Issue 10, October 2024.
Abstract Background Over the past decades, it has become increasingly evident that sleep disturbance contributes to inflammation‐mediated disease, including depression, mainly through activation of the innate immune system and to an increased risk of infections.
Thijs Feuth
wiley   +1 more source

Novel Patient‐Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced Palatability, Controlled Absorption, and Less Variability: High Potential for Pediatric Use

The Journal of Clinical Pharmacology, Volume 64, Issue 10, Page 1295-1303, October 2024.
Abstract Ivermectin has been used since the 1980s as an anthelmintic and antiectoparasite agent worldwide. Currently, the only available oral formulation is tablets designed for adult patients. A patient‐friendly orodispersible tablet formulation designed for pediatric use (CHILD‐IVITAB) has been developed and is entering early phase clinical trials ...
Kim Dao, Michael Buettcher, Klervi Golhen, Jonas Kost, Andreas Schittny, Urs Duthaler, Andrew Atkinson, David Haefliger, Monia Guidi, Carine Bardinet, Haithem Chtioui, Abdelwahab Boulekbache, Thierry Buclin, Jörg Huwyler, Marc Pfister, Laura E. Rothuizen   +15 more
wiley   +1 more source

A Phase 1, Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Trial of AWZ1066S, an Anti‐Wolbachia Candidate Macrofilaricide

Clinical Pharmacology in Drug Development, Volume 13, Issue 9, Page 1071-1081, September 2024.
Abstract AWZ1066S has been developed as a potential treatment for the neglected tropical diseases lymphatic filariasis and onchocerciasis. AWZ1066S targets the Wolbachia bacterial endosymbiont present in the causative nematode parasites. This phase 1, first‐in‐human study aimed to assess the safety and pharmacokinetics of AWZ1066S in healthy human ...
Graham Devereux, Marcin Bula, Karen Tripp, Richard Fitzgerald, Nicola Eraut, Muhammad Salman Alam, Tomoyuki Moriyama, Raku Shinkyo, Lauren Walker, Duolao Wang, Fabian Gusovsky, Jeannette van der Velde, Joseph D. Turner, Weiqian David Hong, Paul M. O'Neill, Mark J. Taylor, Stephen A. Ward   +16 more
wiley   +1 more source

Filariose bancroftiana no Brasil

Revista de Saúde Pública, 1998
Foi feita revisão dos estudos sobre a distribuição geográfica e prevalências da filariose linfática bancroftiana no Brasil. Entre 1951 a 1958 foram realizados inquéritos hemoscópicos e entomológicos no País, sendo a transmissão autóctone comprovada em ...
Rocha Eliana M. M., Fontes Gilberto
doaj   +3 more sources

Mammographic parasitic calcifications in South West Nigeria: prospective and descriptive study

The Pan African Medical Journal, 2013
BACKGROUND: Lymphatic filariasis caused by nematode parasite Wuchereria bancrofti and Brugia Malayi is endemic in the tropics. In Nigeria, 25% of the population is infected. Lymph edema and elephantiasis are the predominant manifestations. Its infrequent
Adenike Temitayo Adeniji-Sofoluwe, Millicent Olubunmi Obajimi, Abideen Olayiwola Oluwasola, Temitope O Soyemi   +3 more
doaj   +1 more source

Selective Peptide Binders to the Perfluorinated Sulfonic Acid Ionomer Nafion

Advanced Functional Materials, Volume 34, Issue 20, May 16, 2024.
Selective non‐covalent binders to technical polymers enable novel approaches to design fuel cell membranes structured at the molecular level. A novel screening method is demonstrated to identify selective peptide binders to Nafion ionomer. Abstract Fuel cells used for transport applications hold polymer membranes as a key element.
Dimitry Schmidt, Patrizia Gartner, Ivan Berezkin, Jens Rudat, Maximilian Bilger, Tom Grünert, Nadine Zimmerer, Philipp Quarz, Philip Scharfer, Julian Brückel, André P. Jung, Pooja Singh, Pooja Pooja, Benno Meier, Mareen Stahlberger, Wilhelm Schabel, Stefan Bräse, Gisela Lanza, Alexander Nesterov‐Mueller   +18 more
wiley   +1 more source

Virulence is associated with daily rhythms in the within‐host replication of the malaria parasite Plasmodium chabaudi

Evolutionary Applications, Volume 17, Issue 5, May 2024.
Abstract Most malaria (Plasmodium spp.) parasite species undergo asexual replication synchronously within the red blood cells of their vertebrate host. Rhythmicity in this intraerythrocytic developmental cycle (IDC) enables parasites to maximise exploitation of the host and align transmission activities with the time of day that mosquito vectors blood ...
Alíz T. Y. Owolabi, Petra Schneider, Sarah E. Reece   +2 more
wiley   +1 more source

Effect of salinity on the oviposition and growth of Ochlerotatus togoi

Ecology and Evolution, Volume 14, Issue 4, April 2024.
Ochlerotatus togoi is a pest that is tolerance to salinity. We conducted experiments on spawning habits and development of Oc. togoi in the range of 0–35 psu. Within this range, the oviposition preference and each growth rate showed different patterns. This study will be used to predict and control the population of Oc. togoi.
Jae Won Choi, Kwang Shik Choi
wiley   +1 more source

Lymphatic filariasis transmission on Mafia Islands, Tanzania: Evidence from xenomonitoring in mosquito vectors. [PDF]

PLoS Neglected Tropical Diseases, 2017
Lymphatic filariasis (LF) is a chronic nematode infection transmitted by mosquitoes and in sub-Saharan Africa it is caused by Wuchereria bancrofti.
Yahya A Derua, Susan F Rumisha, Bernard M Batengana, Demetrius A Max, Grades Stanley, William N Kisinza, Leonard E G Mboera   +6 more
doaj   +1 more source

Isolated perinephric abscess as the initial manifestation of filariasis—an unusual presentation

Clinical Case Reports, Volume 12, Issue 3, March 2024.
Graphical Abstract Key Clinical Message Filariasis may present as an isolated perinephric abscess. Hence, a high index of suspicion should be maintained in endemic settings. Abstract In cases with unexplained fever, eosinophilia and perinephric collection, it is necessary to do detailed infectious disease work up. High index of suspicion is required to
Govind Sharma, Rajat Sachdeva, Shweta Aggarwal, Amogh Verma, Ayush Anand, Ajeet Singh, Prakasini Satapathy   +6 more
wiley   +1 more source