Results 41 to 50 of about 11,005 (258)

Molecular Characterisation of Fungi Populations in the Chronic Wounds of Filarial Lymphedema Patients in Southern Ghana: A Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims Lymphatic filariasis (LF) and associated chronic wounds are of public health concern worldwide. Despite the significant burden of lymphatic filariasis (LF) and its associated chronic wounds, the fungal component of the wound microbiome remains poorly understood. Previous research has primarily focused on bacterial pathogens,
Dzidzor Yawa Ayeke, Priscilla Osei‐Poku, Drake Byamukama, Emmanuel Kobla Atsu Amewu, Arnold Abakah, Abdul Latif Koney Shardow, Susana Makafui Abla Yeboah, Cindy Antwiwaa, Mary Boampomaa Wilson, Solomon Wireko, Amma Larbi, Alexander Kwarteng   +11 more
wiley   +1 more source

An Unusual Presentation of Human Parotid Filariasis

Tropical Medicine and Infectious Disease
Human filariasis caused by Wuchereria bancrofti and Brugia malayi continues to circulate within Northern and Central Thailand and Southern Thailand, respectively.
Tanaya Siripoon, Suppachok Kirdlarp, Polrat Wilairatana, Viravarn Luvira, Prakaykaew Charunwatthana, Parnpen Viriyavejakul, Paron Dekumyoy   +6 more
doaj   +1 more source

Evidence against Wolbachia symbiosis in Loa loa [PDF]

, 2003
BACKGROUND: The majority of filarial nematode species are host to Wolbachia bacterial endosymbionts, although a few including Acanthocheilonema viteae, Onchocerca flexuosa and Setaria equina have been shown to be free of infection. Comparisons of species
Akue, Jean-Paul, Beeching, Nick J, Bianco, Albert E, Egerton, Gill, Enyong, Peter, Hoerauf, Achim, Kläger, Sabine L, McGarry, Helen F, Pfarr, Ken, Taylor, Mark J, Wanji, Samuel   +10 more
core   +2 more sources

Targeting Mitogen‐Activated Protein Kinase‐Activating Death Domain Protein of Brugia malayi for Construction of a Multi‐Epitope Subunit Vaccine Against Lymphatic Filariasis

Medicine Advances, Volume 3, Issue 3, Page 177-192, September 2025.
We focused on the MAP kinase activating death domain (MADD) protein of Brugia malayi as a candidate for a vaccine against lymphatic filariasis (LF). Our results demonstrated a significant increase in the production of memory B‐cells, T‐cells, and antibodies, which are crucial for removing microfilariae from the circulation of infected individuals. This
Paa Kwesi Anfu, Gifty Madjitey, Jennifer Afreh, Arnold Abakah, Prince Dunyo, Prince Manu, Kweku Foh Gyasi, Priscilla Osei‐Poku, Alexander Kwarteng   +8 more
wiley   +1 more source

The global distribution and transmission limits of lymphatic filariasis: past and present. [PDF]

, 2014
BACKGROUND: Lymphatic filariasis (LF) is one of the neglected tropical diseases targeted for global elimination by 2020 and to guide elimination efforts countries have, in recent years, conducted extensive mapping surveys.
Bockarie, Moses J, Brooker, Simon J, Cano, Jorge, Crellen, Thomas, Golding, Nick, Hay, Simon I, Kelly-Hope, Louise A, Lindsay, Steve W, Pullan, Rachel L, Rebollo, Maria P, Soler, Anna   +10 more
core   +6 more sources

Strong Bottlenecks Constrain Adaptive Coevolution in a Host–Parasite Metapopulation

Molecular Ecology, Volume 34, Issue 17, September 2025.
ABSTRACT Although parasites are well‐known for adaptively evolving in order to exploit their hosts, they may experience strong genetic drift during transmission bottlenecks when infecting a new host. Host population structure and host population bottlenecks can also lead to genetic drift effects in parasite populations, constraining their adaptive ...
Pascal Angst, Christoph R. Haag, Frida Ben‐Ami, Peter D. Fields, Dieter Ebert   +4 more
wiley   +1 more source

Focusing nucleic acid-based molecular diagnostics and xenomonitoring approaches for human helminthiases amenable to preventive chemotherapy [PDF]

, 2016
The current mainstay for control of the four major helminth diseases in humans (lymphatic filariasis, onchocerciasis, soil-transmitted helminthiases and schistosomiasis) is with preventive chemotherapy by mass administration of key anthelminthics ...
LaCourse, James, Minetti, Corrado, Reimer, Lisa, Stothard, Russell   +3 more
core   +3 more sources

PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection

European Journal of Immunology, Volume 55, Issue 8, August 2025.
During filarial nematode infection with Litomosoides sigmodontis, PD‐L2 down‐regulates Th2 cell expression of GATA‐3 and Th2 cytokines and enables parasite survival. Concurrently, B cells suppress protective immunity through a mechanism that does not involve PD‐L2.
Johanna A. Knipper, Sharon M. Campbell, Judith E. Allen, Matthew D. Taylor   +3 more
wiley   +1 more source

Integrated Serologic Surveillance of Population Immunity and Disease Transmission. [PDF]

, 2018
Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus,
Arnold, Benjamin F, Lammie, Patrick J, Priest, Jeffrey W, Scobie, Heather M   +3 more
core   +1 more source

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza, Michael Olubusayo Binuyo, Callixte Cyuzuzo, Acsa Igizeneza, Jean Paul Sinumvayo, Oluwaremilekun Grace Ajakaye, Egie Elisha Enabulele, Zororo Chinwadzimba, Ezera Agwu, Nicholas Midzi   +9 more
wiley   +1 more source