Results 81 to 90 of about 11,005 (258)

Urban Lymphatic Filariasis in the Metropolis of\ud Dar es Salaam, Tanzania [PDF]

, 2013
The last decades have seen a considerable increase in urbanization in Sub-Saharan Africa, and it is estimated that over 50% of the population will live in urban areas by 2040.
Malecela, Mwelecele N, Mosha, Franklin W, Mwakitalu, Mbutolwe E, Pedersen, Erling M, Simonsen, Paul E   +4 more
core  

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
A Tarkowski, AL Moncayo, AM Gan, B Min, Cathy Steel, CH Kuo, CM Steppan, D Artis, D Voehringer, DD Taub, DR Herbert, DR Herbert, DR Neill, Edward J. Pearce, F Chen, Gang Chen, GD Thomas, Graham Le Gros, H Helmby, HK Park, HS Jung, J Bethony, J Urban, J Wang, JA Jackson, Jessica C. Jang, JF Urban Jr, JI Odegaard, JJ Reece, Josiah I. Chung, JT Pesce, K Migita, KT Cuenco, L Boring, L Le Goff, L Patel, LC Osborne, M Lehrke, M Lehrke, M Qatanani, Mali Camberis, Mark A. Barnes, Meera G. Nair, MG Nair, MG Nair, MG Nair, Mitchell A. Lazar, MM Pirvulescu, MP Reilly, N Silswal, P Loke, PF Weller, Philip J. Cooper, PJ George, PJ Hotez, R Anuradha, RM Anthony, RT Semnani, RZ Yang, S Babu, S Babu, S Babu, S Babu, S Jiang, S Lee, Spencer H. Wang, Thomas B. Nutman, TT MacDonald, W He, Y Benomar, YY Hsieh   +70 more
core   +5 more sources

Novel Patient‐Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced Palatability, Controlled Absorption, and Less Variability: High Potential for Pediatric Use

The Journal of Clinical Pharmacology, Volume 64, Issue 10, Page 1295-1303, October 2024.
Abstract Ivermectin has been used since the 1980s as an anthelmintic and antiectoparasite agent worldwide. Currently, the only available oral formulation is tablets designed for adult patients. A patient‐friendly orodispersible tablet formulation designed for pediatric use (CHILD‐IVITAB) has been developed and is entering early phase clinical trials ...
Kim Dao, Michael Buettcher, Klervi Golhen, Jonas Kost, Andreas Schittny, Urs Duthaler, Andrew Atkinson, David Haefliger, Monia Guidi, Carine Bardinet, Haithem Chtioui, Abdelwahab Boulekbache, Thierry Buclin, Jörg Huwyler, Marc Pfister, Laura E. Rothuizen   +15 more
wiley   +1 more source

Perspectivas da municipalização do controle da filariose linfática na região metropolitana do Recife Views on the municipalization of lymphatic filariasis control in greater metropolitan Recife

Cadernos de Saúde Pública, 1999
A filariose linfática resulta da infecção por três nematódeos: Brugia malayi, Brugia timori e Wuchereria bancrofti. Atingindo países considerados em desenvolvimento, é mais distribuída em áreas urbanas.
Amélia Maciel, André F. Furtado, Keyla B. F. Marzochi   +2 more
doaj   +1 more source

A Phase 1, Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Trial of AWZ1066S, an Anti‐Wolbachia Candidate Macrofilaricide

Clinical Pharmacology in Drug Development, Volume 13, Issue 9, Page 1071-1081, September 2024.
Abstract AWZ1066S has been developed as a potential treatment for the neglected tropical diseases lymphatic filariasis and onchocerciasis. AWZ1066S targets the Wolbachia bacterial endosymbiont present in the causative nematode parasites. This phase 1, first‐in‐human study aimed to assess the safety and pharmacokinetics of AWZ1066S in healthy human ...
Graham Devereux, Marcin Bula, Karen Tripp, Richard Fitzgerald, Nicola Eraut, Muhammad Salman Alam, Tomoyuki Moriyama, Raku Shinkyo, Lauren Walker, Duolao Wang, Fabian Gusovsky, Jeannette van der Velde, Joseph D. Turner, Weiqian David Hong, Paul M. O'Neill, Mark J. Taylor, Stephen A. Ward   +16 more
wiley   +1 more source

Assessment of family and neighbors of an individual infected with Wuchereria bancrofti from a non-endemic area in the city of Maceió, Brazil [PDF]

, 2010
Anderson B. Leite, Ana RV de Lima, Renata B Leite, Rafael Vital dos Santos, Johnathan EL Gonçalves, Eliana MM Rocha, Gilberto Fontes   +6 more
openalex   +2 more sources

Wuchereria bancrofti Lymphatic Filariasis, Barrancabermeja, Colombia, 2023

Emerging Infectious Diseases
We describe a recent case of lymphatic filariasis in Colombia caused by Wuchereria bancrofti nematodes. Our study combines clinical-epidemiologic findings with phylogenetic data.
José A. Suárez, Jose A. Vargas-Soler, Laura Isabel Manosalva-Arciniegas, Stephanie Becerra-González, Angie L. Ramirez, Tatiana Cáceres, Nicolas Luna, Juan David Ramírez, Alberto Paniz-Mondolfi   +8 more
doaj   +1 more source

Selective Peptide Binders to the Perfluorinated Sulfonic Acid Ionomer Nafion

Advanced Functional Materials, Volume 34, Issue 20, May 16, 2024.
Selective non‐covalent binders to technical polymers enable novel approaches to design fuel cell membranes structured at the molecular level. A novel screening method is demonstrated to identify selective peptide binders to Nafion ionomer. Abstract Fuel cells used for transport applications hold polymer membranes as a key element.
Dimitry Schmidt, Patrizia Gartner, Ivan Berezkin, Jens Rudat, Maximilian Bilger, Tom Grünert, Nadine Zimmerer, Philipp Quarz, Philip Scharfer, Julian Brückel, André P. Jung, Pooja Singh, Pooja Pooja, Benno Meier, Mareen Stahlberger, Wilhelm Schabel, Stefan Bräse, Gisela Lanza, Alexander Nesterov‐Mueller   +18 more
wiley   +1 more source

What's in your next-generation sequence data? An exploration of unmapped DNA and RNA sequence reads from the bovine reference individual. [PDF]

, 2015
BackgroundNext-generation sequencing projects commonly commence by aligning reads to a reference genome assembly. While improvements in alignment algorithms and computational hardware have greatly enhanced the efficiency and accuracy of alignments, a ...
Alexander, Leeson J, Decker, Jared E, Kim, JaeWoo, Medrano, Juan F, Schnabel, Robert D, Schroeder, Steven G, Sonstegard, Tad S, Taylor, Jeremy F, Tizioto, Polyana C, Whitacre, Lynsey K   +9 more
core   +1 more source

A cross-sectional study of the filarial and Leishmania co-endemicity in two ecologically distinct settings in Mali

Parasites & Vectors, 2018
Background Filariasis and leishmaniasis are two neglected tropical diseases in Mali. Due to distribution and associated clinical features, both diseases are of concern to public health.
Moussa Brema Sangare, Yaya Ibrahim Coulibaly, Siaka Yamoussa Coulibaly, Michel Emmanuel Coulibaly, Bourama Traore, Ilo Dicko, Ibrahim Moussa Sissoko, Sibiry Samake, Sekou Fantamady Traore, Thomas Bruce Nutman, Jesus Gilberto Valenzuela, Ousmane Faye, Shaden Kamhawi, Fabiano Oliveira, Roshanak Tolouei Semnani, Seydou Doumbia   +15 more
doaj   +1 more source