Results 81 to 90 of about 7,474,775 (237)

320x240 GaAs pixel detectors with improved X-ray imaging quality

, 2001
We report on gain and offset corrections for GaAs X-ray pixel detectors, which were hybridised to silicon CMOS readout integrated circuits (ROICs). The whole detector array contains 320 x 240 square-shaped pixels with a pitch of 38 mum.
Martijn, H., P. Helander, V. O’Shea, R. Irsigler, M. Östlund, Fröjdh, Christer,, C. Fröjdh, Östlund, M, Helander, P, Smith, K M, Fakoor-Biniaz, Z., D. Meikle, Z. Fakoor-Biniaz, Andersson, J, J. Andersson, H. Martijn, Smith, K., Alverbro, J, J. Alverbro, Meikele, D, Alverbro, J., Meikle, D., Martijn, H, O'Shea, V., K. Smith, Frojdh, C., Ostlund, M., Helander, P., Irsigler, R, Andersson, J., Fakoor-Biniaz, Z, Irsigler, R., O'Shea, V   +32 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

A critical consideration of x-ray detectors based on Ga2O3: Excitation, carrier transport mechanisms, and performance standardization [PDF]

APL Materials
X-ray detection underpins a wide range of applications in medicine, security, industrial inspection, scientific research for non-destructive imaging, and material analysis.
Alfred Moore, Daniel A. Lamb, Lijie Li, Oliver Fox, Kawal Sawhney, Ciaran Llewelyn, Jon E. Evans, Saqib Rafique, Tiantian Chai, John Harrington, Zabeada Aslam, Andrew P. Brown, Rik Drummond-Brydson, Yaonan Hou   +13 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Semiconductor X-ray detectors

, 2014
Identifying and measuring the elemental x-rays released when materials are examined with particles (electrons, protons, alpha particles, etc.) or photons (x-rays and gamma rays) is still considered to be the primary analytical technique for routine and ...
Lowe, Barrie Glyn, Sareen, Robert Anthony   +1 more
core  

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Low-noise CMOS Charge Preamplifier for X-ray Spectroscopy Detectors

, 2010
The development of radiation detectors for high-resolution high-rate X-ray spectroscopy is strictly related to the continuous improvement of the performances of the related front-end readout electronics.
C Fiorini, FIORINI, CARLO ETTORE, FRIZZI, TOMMASO, GREPPI, ANDREA, A Longoni, R Nava, NAVA, RICCARDO, BOMBELLI, LUCA, L Bombelli, T Frizzi, LONGONI, ANTONIO FRANCESCO, A Greppi   +11 more
core   +1 more source