Results 41 to 50 of about 1,010,031 (280)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The ASTRO-H X-ray Observatory

, 2012
The joint JAXA/NASA ASTRO-H mission is the sixth in a series of highly successful X-ray missions initiated by the Institute of Space and Astronautical Science (ISAS).
Aarts, Henri, Aharonian, Felix, Akamatsu, Hiroki, Akimoto, Fumie, Allen, Steve, Anabuki, Naohisa, Angelini, Lorella, Arnaud, Keith, Asai, Makoto, Audard, Marc, Awaki, Hisamitsu, Azzarello, Philipp, Baluta, Chris, Bamba, Aya, Bando, Nobutaka, Bautz, Mark, Blandford, Roger, Boyce, Kevin, Brown, Greg, Cackett, Ed, Chernyakova, Mara, Coppi, Paolo, Costantini, Elisa, de Plaa, Jelle, de Vries, Cor, den Herder, Jan-Willem, DiPirro, Michael, Done, Chris, Dotani, Tadayasu, Doty, John, Ebisawa, Ken, Eckart, Megan, Enoto, Teruaki, Ezoe, Yuichiro, Fabian, Andrew, Ferrigno, Carlo, Foster, Adam, Fujimoto, Ryuichi, Fukazawa, Yasushi, Funk, Stefan, Furuzawa, Akihiro, Galeazzi, Massimiliano, Gallo, Luigi, Gandhi, Poshak, Gendreau, Keith, Gilmore, Kirk, Haas, Daniel, Haba, Yoshito, Hamaguchi, Kenji, Hatsukade, Isamu, Hayashi, Takayuki, Hayashida, Kiyoshi, Hiraga, Junko, Hirose, Kazuyuki, Hornschemeier, Ann, Hoshino, Akio, Hughes, John, Hwang, Una, Iizuka, Ryo, Inoue, Yoshiyuki, Ishibashi, Kazunori, Ishida, Manabu, Ishimura, Kosei, Ishisaki, Yoshitaka, Ito, Masayuki, Iwata, Naoko, Iyomoto, Naoko, Kaastra, Jelle, Kallman, Timothy, Kamae, Tuneyoshi, Kataoka, Jun, Katsuda, Satoru, Kawahara, Hajime, Kawaharada, Madoka, Kawai, Nobuyuki, Kawasaki, Shigeo, Kelley, Richard, Khangaluyan, Dmitry, Kilbourne, Caroline, Kimura, Masashi, Kinugasa, Kenzo, Kitamoto, Shunji, Kitayama, Tetsu, Kohmura, Takayoshi, Kokubun, Motohide, Kosaka, Tatsuro, Koujelev, Alex, Koyama, Katsuji, Krimm, Hans, Kubota, Aya, Kunieda, Hideyo, LaMassa, Stephanie, Laurent, Philippe, Lebrun, Francois, Leutenegger, Maurice, Limousin, Olivier, Loewenstein, Michael, Long, Knox, Lumb, David, Madejski, Grzegorz, Maeda, Yoshitomo, Makishima, Kazuo, Marchand, Genevieve, Markevitch, Maxim, Matsumoto, Hironori, Matsushita, Kyoko, McCammon, Dan, McNamara, Brian, Miller, Eric, Miller, Jon, Mineshige, Shin, Minesugi, Kenji, Mitsuda, Kazuhisa, Mitsuishi, Ikuyuki, Miyazawa, Takuya, Mizuno, Tsunefumi, Mori, Hideyuki, Mori, Koji, Mukai, Koji, Murakami, Hiroshi, Murakami, Toshio, Mushotzky, Richard, Nagano, Hosei, Nagino, Ryo, Nakagawa, Takao, Nakajima, Hiroshi, Nakamori, Takeshi, Nakazawa, Kazuhiro, Namba, Yoshiharu, Natsukari, Chikara, Nishioka, Yusuke, Nobukawa, Masayoshi, Nomachi, Masaharu, O'Dell, Steve, Odaka, Hirokazu, Ogawa, Hiroyuki, Ogawa, Mina, Ogi, Keiji, Ohashi, Takaya, Ohno, Masanori, Ohta, Masayuki, Okajima, Takashi, Okamoto, Atsushi, Okazaki, Tsuyoshi, Ota, Naomi, Ozaki, Masanobu, Paerels, Fritzs, Paltani, Stéphane, Parmar, Arvind, Petre, Robert, Pohl, Martin, Porter, F. Scott, Ramsey, Brian, Reis, Rubens, Reynolds, Christopher, Russell, Helen, Safi-Harb, Samar, Sakai, Shin-ichiro, Sameshima, Hiroaki, Sanders, Jeremy, Sato, Goro, Sato, Kosuke, Sato, Rie, Sato, Yohichi, Sawada, Makoto, Serlemitsos, Peter, Seta, Hiromi, Shibano, Yasuko, Shida, Maki, Shimada, Takanobu, Shinozaki, Keisuke, Shirron, Peter, Simionescu, Aurora, Simmons, Cynthia, Smith, Randall, Sneiderman, Gary, Soong, Yang, Stawarz, Lukasz, Sugawara, Yasuharu, Sugita, Hiroyuki, Sugita, Satoshi, Szymkowiak, Andrew, Tajima, Hiroyasu, Takahashi, Hiromitsu, Takahashi, Tadayuki, Takeda, Shin-ichiro, Takei, Yoh, Tamagawa, Toru, Tamura, Keisuke, Tamura, Takayuki, Tanaka, Takaaki, Tanaka, Yasuo, Tashiro, Makoto, Tawara, Yuzuru, Terada, Yukikatsu, Terashima, Yuichi, Tombesi, Francesco, Tomida, Hiroshi, Tsuboi, Yohko, Tsujimoto, Masahiro, Tsunemi, Hiroshi, Tsuru, Takeshi, Uchida, Hiroyuki, Uchiyama, Hideki, Uchiyama, Yasunobu, Ueda, Yoshihiro, Ueno, Shiro, Uno, Shinichiro, Urry, Meg, Ursino, Eugenio, Wada, Atsushi, Watanabe, Shin, Werner, Norbert, White, Nicholas, Yamada, Shinya, Yamada, Takahiro, Yamaguchi, Hiroya, Yamasaki, Noriko, Yamauchi, Makoto, Yamauchi, Shigeo, Yatsu, Yoichi, Yonetoku, Daisuke, Yoshida, Atsumasa, Yuasa, Takayuki   +223 more
core   +1 more source

RESEARCH MARKETING TOOLS, WHICH IMPROVE THE LIFE OF PEOPLE WITH DISABILITIES [PDF]

, 2002
Parabolic refractive X-ray lenses are optical components, especially suitable for third-generation synchrotron radiation sources. This article describes the status of the development of our lenses and illustrates the possibilities for micrometre and ...
Benner, Boris, Gerhardus, A., Günzler, Til Florian, Kuhlmann, Marion, Lengeler, Bruno, Meyer, J., Schroer, Christian, Zimprich, C.   +7 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Convection-enhanced water evaporation

AIP Advances, 2011
Water vapor is lighter than air; this can enhance water evaporation by triggering vapor convection but there is little evidence. We directly visualize evaporation of nanoliter (2 to 700 nL) water droplets resting on silicon wafer in calm air using a high-
B. M. Weon, J. H. Je, C. Poulard
doaj   +1 more source

Alpha shapes: determining 3D shape complexity across morphologically diverse structures

BMC Evolutionary Biology, 2018
Background Following recent advances in bioimaging, high-resolution 3D models of biological structures are now generated rapidly and at low-cost. To use this data to address evolutionary and ecological questions, an array of tools has been developed to ...
James D. Gardiner, Julia Behnsen, Charlotte A. Brassey   +2 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Polymer composite microtube array produced by meniscus-guided approach

AIP Advances, 2013
Single freestanding microtubes of poly(methyl methacrylate)/polypyrrole (PMMA/PPy) are produced based on a meniscus-guided approach. A ring-deposit of nanoparticles is first formed in a meniscus solution of PMMA/PPy nanoparticles by outward liquid flow ...
Kyu Hwang Won, Byung Mook Weon, Jung Ho Je   +2 more
doaj   +1 more source

Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation

IEEE Journal of Translational Engineering in Health and Medicine, 2014
Real-time imaging is required to guide minimally invasive catheter-based cardiac interventions. While transesophageal echocardiography allows for high-quality visualization of cardiac anatomy, X-ray fluoroscopy provides excellent visualization of devices.
Aruna V. Arujuna, R. James Housden, Yingliang Ma, Ronak Rajani, Gang Gao, Niels Nijhof, Pascal Cathier, Roland Bullens, Geert Gijsbers, Victoria Parish, Stamatis Kapetanakis, Jane Hancock, C. Aldo Rinaldi, Michael Cooklin, Jaswinder Gill, Martyn Thomas, Mark D. O'neill, Reza Razavi, Kawal S. Rhode   +18 more
doaj   +1 more source

Quantitative Imaging of Single, Unstained Viruses with Coherent X-rays

, 2008
Since Perutz, Kendrew and colleagues unveiled the structure of hemoglobin and myoglobin based on X-ray diffraction analysis in the 1950s, X-ray crystallography has become the primary methodology used to determine the 3D structure of macromolecules ...
A. C. Steven, Adrian Mancuso, Bagrat Amirbekian, Changyong Song, Huaidong Jiang, J. Kirz, Jianwei Miao, Li Peng, Ren Sun, Sanket S. Shah, Tetsuya Ishikawa, Z. Hong Zhou   +11 more
core   +1 more source