Results 51 to 60 of about 9,583,295 (252)

Two-view topogram-based anatomy-guided CT reconstruction for prospective risk minimization

Scientific Reports
To facilitate a prospective estimation of the effective dose of an CT scan prior to the actual scanning in order to use sophisticated patient risk minimizing methods, a prospective spatial dose estimation and the known anatomical structures are required.
Chang Liu, Laura Klein, Yixing Huang, Edith Baader, Michael Lell, Marc Kachelrieß, Andreas Maier   +6 more
doaj   +1 more source

Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation

IEEE Journal of Translational Engineering in Health and Medicine, 2014
Real-time imaging is required to guide minimally invasive catheter-based cardiac interventions. While transesophageal echocardiography allows for high-quality visualization of cardiac anatomy, X-ray fluoroscopy provides excellent visualization of devices.
Aruna V. Arujuna, R. James Housden, Yingliang Ma, Ronak Rajani, Gang Gao, Niels Nijhof, Pascal Cathier, Roland Bullens, Geert Gijsbers, Victoria Parish, Stamatis Kapetanakis, Jane Hancock, C. Aldo Rinaldi, Michael Cooklin, Jaswinder Gill, Martyn Thomas, Mark D. O'neill, Reza Razavi, Kawal S. Rhode   +18 more
doaj   +1 more source

View synthesis for kinetic depth X-ray imaging [PDF]

, 2012
This thesis reports the development and analysis of feature based synthesis of transmission X-ray images. The synthetic imagery is formed through matching and morphing or warping line-scan format images produced by a novel multi-view X-ray machine.
Abusaeeda, OA
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions

Nature Communications
Understanding protein motion within the cell is crucial for predicting reaction rates and macromolecular transport in the cytoplasm. A key question is how crowded environments affect protein dynamics through hydrodynamic and direct interactions at ...
Anita Girelli, Maddalena Bin, Mariia Filianina, Michelle Dargasz, Nimmi Das Anthuparambil, Johannes Möller, Alexey Zozulya, Iason Andronis, Sonja Timmermann, Sharon Berkowicz, Sebastian Retzbach, Mario Reiser, Agha Mohammad Raza, Marvin Kowalski, Mohammad Sayed Akhundzadeh, Jenny Schrage, Chang Hee Woo, Maximilian D. Senft, Lara Franziska Reichart, Aliaksandr Leonau, Prabhu Rajaiah Prince, William Chèvremont, Tilo Seydel, Jörg Hallmann, Angel Rodriguez-Fernandez, Jan-Etienne Pudell, Felix Brausse, Ulrike Boesenberg, James Wrigley, Mohamed Youssef, Wei Lu, Wonhyuk Jo, Roman Shayduk, Trey Guest, Anders Madsen, Felix Lehmkühler, Michael Paulus, Fajun Zhang, Frank Schreiber, Christian Gutt, Fivos Perakis   +40 more
doaj   +1 more source

Polymer composite microtube array produced by meniscus-guided approach

AIP Advances, 2013
Single freestanding microtubes of poly(methyl methacrylate)/polypyrrole (PMMA/PPy) are produced based on a meniscus-guided approach. A ring-deposit of nanoparticles is first formed in a meniscus solution of PMMA/PPy nanoparticles by outward liquid flow ...
Kyu Hwang Won, Byung Mook Weon, Jung Ho Je   +2 more
doaj   +1 more source

Alpha shapes: determining 3D shape complexity across morphologically diverse structures

BMC Evolutionary Biology, 2018
Background Following recent advances in bioimaging, high-resolution 3D models of biological structures are now generated rapidly and at low-cost. To use this data to address evolutionary and ecological questions, an array of tools has been developed to ...
James D. Gardiner, Julia Behnsen, Charlotte A. Brassey   +2 more
doaj   +1 more source

Nano Organic Co‐Crystal Scintillator for X‐ray Imaging

Small Structures, 2023
Traditional‐metal‐containing scintillators are widely used in X‐ray imaging due to their efficient X‐ray absorption and output of visible light. However, they suffer from heavy‐metal toxicity, environmental stability, harsh preparation, and afterglow ...
Qisheng Sun, Hongyun Wang, Jing Li, Fei Li, Weigang Zhu, Xiaotao Zhang, Qiushui Chen, Huanghao Yang, Wenping Hu   +8 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Towards time-resolved multiscale and multimodal imaging

npj Imaging
Current biomedical imaging focuses on spatial detail but overlooks time, limiting our understanding of disease progression. There is an unmet need for temporal atlases that align multiscale and multimodal data across defined timepoints, enabling dynamic ...
Jishizhan Chen
doaj   +1 more source