Results 41 to 50 of about 9,583,295 (252)
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Phase contrast imaging with a laboratory-based microfocus X-ray source [PDF]
This project looks at the design of an in-line X-ray phase contrast imaging system, based around the Bede Microsource®, on a suitable scale for imaging small pathological samples. The system is applied to two test objects to assess feasibility of its use
Kelly, Kathryn L, Kelly, Kathryn L.
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Algorithms for joint activity–attenuation estimation from positron emission tomography scatter
Background Attenuation correction in positron emission tomography remains challenging in the absence of measured transmission data. Scattered emission data may contribute missing information, but quantitative scatter-to-attenuation (S2A) reconstruction ...
Yannick Berker +2 more
doaj +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Progress on multi-order hard x-ray imaging with multilayer zone plates
Hard x-ray focusing and imaging on the few nano metre scale has gained a lot of attraction in the last couple of years. Thanks to new developments in fabrication and inspection of high-N.A.
Huang +20 more
core +1 more source
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Convection-enhanced water evaporation
Water vapor is lighter than air; this can enhance water evaporation by triggering vapor convection but there is little evidence. We directly visualize evaporation of nanoliter (2 to 700 nL) water droplets resting on silicon wafer in calm air using a high-
B. M. Weon, J. H. Je, C. Poulard
doaj +1 more source
x-Ray Imaging with Coherent Sources
2.08.1 Introduction 2.08.1.1 x-Rays as Waves 2.08.1.2 Coherent x-Ray Sources 2.08.2 Phase-Sensitive Techniques for x-Ray Imaging 2.08.2.1 Propagation-Based Phase-Contrast Imaging 2.08.2.1.1 Methods 2.08.2.1.2 Applications 2.08.2.2 Analyzer ...
RIGON, LUIGI, L. Rigon
core +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source

