Results 31 to 40 of about 150,726,015 (302)

Model-in-the-Loop Simulation of Mechanical Ventilation in Neonates

open access: yesCurrent Directions in Biomedical Engineering
Preterm neonates often require mechanical ventilation due to immaturity of the respiratory system at birth. Physiological Closed-Loop Control (PCLC) has the potential to improve therapy and relieve clinical staff.
Pfannschmidt Valerie   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Holomorphy of Osborn loops

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science, 2015
Let (L, ·) be any loop and let A(L) be a group of automorphisms of (L, ·) such that α and φ are elements of A(L). It is shown that, for all x, y, z ∈ L, the A(L)-holomorph (H, ○) = H(L) of (L, ·) is an Osborn loop if and only if xα(yz · xφ−1) = xα(yxλ ...
Isere Abednego Orobosa   +2 more
doaj   +1 more source

From Jacobi off-shell currents to integral relations

open access: yesJournal of High Energy Physics, 2017
In this paper, we study off-shell currents built from the Jacobi identity of the kinematic numerators of gg → X with X=ss,qq¯,gg $$ X=ss,q\overline{q}, gg $$.
José Llanes Jurado   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

line up and taste this [PDF]

open access: yes, 1999
Listing for Too Close To Fire from The Loop.

core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

X-in-Loop Proof-of-Concept Test Platform for Commercial Vehicle Intelligent Braking ECPBS and Its Application

open access: yesIEEE Access
This paper presents an X-in-Loop test platform designed for the Proof-of-Concept testing of intelligent braking ECPBS in commercial vehicle. Firstly, the concept of intelligent braking is introduced, outlining its research scope and defining the ...
Ran Zhao   +6 more
doaj   +1 more source

X-Ray and Gamma-Ray Observations of the Fermi Bubbles and NPS/Loop I Structures

open access: yesGalaxies, 2018
The Fermi bubbles were possibly created by large injections of energy into the Galactic Center (GC), either by an active galactic nucleus (AGN) or by nuclear starburst more than ~10 Myr ago.
Jun Kataoka   +5 more
doaj   +1 more source

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