Results 101 to 110 of about 8,781 (227)

Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production. [PDF]

, 1998
We investigated the role of Bruton's tyrosine kinase (Btk) in FcepsilonRI-dependent activation of mouse mast cells, using xid and btk null mutant mice.
Alt, FW, Galli, SJ, Goldfeld, AE, Han, W, Hartman, SE, Hata, D, Inagaki, N, Kawakami, T, Kawakami, Y, Khan, WN, Kitamura, T, Lantz, CS, Maeda-Yamamoto, M, Miura, T, Nagai, H, Witte, ON, Yao, L   +16 more
core  

Characterization of a CD38-like 78-kilodalton soluble protein released from B cell lines derived from patients with X-linked agammaglobulinemia. [PDF]

, 1998
Roberto Mallone, S Ferrua, M. Morra, Elena Zocchi, Kapil Mehta, L. D. Notarangelo, Fabio Malavasi   +6 more
openalex   +1 more source

GRANULOPOIESIS IN X-LINKED AGAMMAGLOBULINEMIA PATIENTS: THE EFFECTS OF IN VITRO AND IN VIVO IMMUNOGLOBULINES 60 [PDF]

, 1997
Serge Gradstein, Talia Hahn, D Shtoger, Yoram Barak   +3 more
openalex   +1 more source

Delayed diagnosis of X-linked agammaglobulinaemia in a boy with recurrent meningitis

BMC Neurology, 2019
Background X-linked agammaglobulinaemia (XLA) is a rare inherited primary immunodeficiency disease characterized by the B cell developmental defect, caused by mutations in the gene coding for Bruton’s tyrosine kinase (BTK), which may cause serious ...
Ya-Ni Zhang, Yuan-Yuan Gao, Si-Da Yang, Bin-Bin Cao, Ke-Lu Zheng, Ping Wei, Lian-Feng Chen, Wen-Xiong Chen   +7 more
doaj   +1 more source

Mutations in topoisomerase IIβ result in a B cell immunodeficiency. [PDF]

, 2019
B cell development is a highly regulated process involving multiple differentiation steps, yet many details regarding this pathway remain unknown. Sequencing of patients with B cell-restricted immunodeficiency reveals autosomal dominant mutations in ...
Austin, Caroline A, Booshehri, Laela M, Broderick, Lori, Brydges, Susannah D, Cowell, Ian G, Croker, Ben A, Frazer, Kelly A, Gebauer, Corinna, Guaderrama, Marisela, Hakonarson, Hakon, Harr, Margaret, Hoffman, Hal M, Hügle, Boris, Kucharova, Karolina, Li, Dong, McGeough, Matthew D, Patel, Niraj C, Putnam, Christopher D, Wang, Jian, Xu, Xun, Yost, Shawn, Zackai, Elaine, Zhang, Jianguo   +22 more
core  

Profound reduction of mature B cell numbers, reactivities and serum lg levels in mice which simultaneously carry the XID and CD40 deficiency gense [PDF]

, 2017
It has been known for some time that single mutant nude or CD40T mice have apparently normal numbers of cells in the precursor compartments of bone marrow and the mature B cell compartments of the periphery.
Andersson, Jan, Kamanaka, Masahito, Kikutani, Hitoshi, Kishimoto, Tadamitsu, Melchers, Fritz, Oka, Yoshiro, Rolink, Antonius G., Uchida, Junji, Yasui, Teruhito   +8 more
core  

Stability and peptide binding specificity of Btk SH2 domain: Molecular basis for X‐linked agammaglobulinemia [PDF]

, 2000
Shiou‐Ru Tzeng, Ming‐Tao Pai, Chih‐Wei Wu, Jya‐Wei Cheng, Feng‐Di T. Lung, Peter P. Roller, Benfang Lei, Chih‐Jen Wei, Shiao‐Chun Tu, Shi‐Han Chen, Wen‐Jue Soong   +10 more
openalex   +1 more source

High Production of IL-18 by Dendritic Cells Induced by Sera from Patients with Primary Antibody Deficiency

Iranian Journal of Allergy, Asthma and Immunology, 2007
Predominantly antibody deficiencies are a category of primary immunodeficiency diseases, which consist of several rare disorders such as common variable immunodeficiency (CVID) and X-linked agammaglobulinemia (XLA).
Maryam Nourizadeh, Asghar Aghamohammadi, Seyed Mohammad Moazzeni, Mahdi Mahdavi, Nima Rezaei, Jamshid Hadjati   +5 more
doaj  

Bruton tyrosine kinase (BTK) in X-linked agammaglobulinemia (XLA) [PDF]

, 2000
Mauno Vihinen
openalex   +1 more source

Molecular studies of X-linked agammaglobulinemia

, 2012
published_or_final_version ; Paediatrics ; Master ; Master of ...
openaire   +3 more sources