Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics. [PDF]
, 2015 Amyloid precursor protein knockout mice (APP-KO) have impaired differentiation of amacrine and horizontal cells. APP is part of a gene family and its paralogue amyloid precursor-like protein 2 (APLP2) has both shared as well as distinct expression ...
Abitbol, M. +15 more
core +7 more sources
Two Sides of the Same Coin : Unravelling the role of transcription factors and miRNAs in activated monocytes, macrophages and microglia [PDF]
, 2012 This thesis focusses on understanding the role of three transcriptions factors, namely ATF3, EGR3 and PU.1, and also microRNA-146a, involved in the activation of monocytes, macrophages and microglia in pathological conditions, which are thought to be ...
Weigelt, K. (Karin)
core +2 more sources
Ocular manifestations of Sturge–Weber syndrome: pathogenesis, diagnosis, and management [PDF]
, 2016 Sturge-Weber syndrome has been included in the group of phakomatoses that is characterized by hamartomas involving the brain, skin, and eyes. The characteristic facial port-wine stain, involving the first branch of the trigeminal nerve and the embryonic ...
Abdolrahimzadeh, Solmaz +4 more
core +1 more source
Bilateral foveal retinoschisis accompanying unilateral peripheral retinoschisis
Indian Journal of Ophthalmology, 2014 X-linked juvenile retinoschisis is a rare hereditary retinal disease characterized by a tangential splitting of the neurosensory retina which may cause early-onset visual impairment.
Nilufer Kocak +2 more
doaj +1 more source
BMC Ophthalmology, 2020 Background Peripheral Retinal neovascularization is well-described as a complication of X-linked retinoschisis, but less often observed in myopic and primary retinoschisis.
Mingyue Luo +3 more
doaj +1 more source
Retinitis pigmentosa, retinoskiisi ja Usherin oireyhtymä : systemaattinen kirjallisuuskatsaus periytyvien verkkokalvorappeumien uusimmista hoitokäytännöistä [PDF]
, 2017 Opinnäytetyön tarkoituksena on koota systemaattinen kirjallisuuskatsaus suomalaisessa väestössä esiintyvistä yleisimmistä perinnöllisistä verkkokalvorappeumista ja niiden viimeaikaisista hoitoihin liittyvistä tutkimuksista. Opinnäytetyö käsittelee kolmea
Ahokas, Aino, Haavisto, Annika
core
Distinctive Mechanisms and Patterns of Exudative Versus Tractional Intraretinal Cystoid Spaces as Seen With Multimodal Imaging. [PDF]
, 2020 PurposeTo determine clear-cut distinctions between tractional and exudative intraretinal cystoid spaces subtypes.DesignRetrospective, multicenter, observational case series.MethodsA cohort of patients diagnosed with intraretinal cystoid spaces and imaged
Au, Adrian +9 more
core
Nanotherapy for Neural Retinal Regeneration
Advanced Science, Volume 12, Issue 24, June 26, 2025.Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu +11 more
wiley +1 more source
Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application
Journal of Medical Virology, Volume 97, Issue 6, June 2025.ABSTRACT Adeno‐associated virus (AAV) is a non‐enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gene delivery system in clinical delivery systems with unique and multiple advantages, such as ...
Ling Yin +6 more
wiley +1 more source
Clinical manifestation and genetic analysis in Chinese early onset X‐linked retinoschisis
Molecular Genetics & Genomic Medicine, 2020 Background X‐linked retinoschisis (XLRS) is one type of retinal dystrophy leading to the schisis of the neural retina and causing reduced visual acuity.
Li Huang +7 more
doaj +1 more source