Results 71 to 80 of about 7,532,788 (147)
BMC Ophthalmology, 2020 Background Peripheral Retinal neovascularization is well-described as a complication of X-linked retinoschisis, but less often observed in myopic and primary retinoschisis.
Mingyue Luo +3 more
doaj +1 more source
Convergence of Human Genetics and Animal Studies: Gene Therapy for X-Linked Retinoschisis. [PDF]
, 2015 Retinoschisis is an X-linked recessive genetic disease that leads to vision loss in males. X-linked retinoschisis (XLRS) typically affects young males; however, progressive vision loss continues throughout life. Although discovered in 1898 by Haas in two
Bush, Ronald A +2 more
core +1 more source
Nanotherapy for Neural Retinal Regeneration
Advanced Science, Volume 12, Issue 24, June 26, 2025.Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu +11 more
wiley +1 more source
Clinical manifestation and genetic analysis in Chinese early onset X‐linked retinoschisis
Molecular Genetics & Genomic Medicine, 2020 Background X‐linked retinoschisis (XLRS) is one type of retinal dystrophy leading to the schisis of the neural retina and causing reduced visual acuity.
Li Huang +7 more
doaj +1 more source
Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application
Journal of Medical Virology, Volume 97, Issue 6, June 2025.ABSTRACT Adeno‐associated virus (AAV) is a non‐enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gene delivery system in clinical delivery systems with unique and multiple advantages, such as ...
Ling Yin +6 more
wiley +1 more source
Refractory macular edema in X-linked juvenile retinoschisis [PDF]
, 2019 X-linked juvenile retinoschisis (XLRS) is one of the most common X-linked inherited, bilateral vitreoretinal dystrophiesaffecting males in the first two decades of life.
Rejdak, Robert; Department of Surgery/Ophthalmology, King Hussein Cancer Center (KHCC), Amman, Jordan +1 more
core +1 more source
Journal of Clinical Ophthalmology and ResearchX-linked retinoschisis (XLRS) is an inherited retinal dystrophy caused by mutations in the RS1 gene, typically presenting in young males with bilateral foveal schisis and variable peripheral involvement.
Ruchi Shukla +4 more
doaj +1 more source
Clinical Genetics, Volume 107, Issue 6, Page 600-611, June 2025.This study provides clinical practice guidelines to streamline genetic testing for inherited retinal dystrophies (IRDs), underscoring the critical role of molecular diagnosis in enhancing patient care. These recommendations aim to elevate diagnostic accuracy, guide therapeutic decisions, and ultimately improve patient outcomes, marking a significant ...
João Pedro Marques +6 more
wiley +1 more source
X-linked juvenile retinoschisis in a black South African: A case report
African Vision and Eye Health, 2019 X-linked juvenile retinoschisis (XLRS) has been well-documented in Finnish and other white populations. This case report illustrates a well-recognised condition in a rare population group.
Katherine Rafferty, Aubrey Makgotloe
doaj +1 more source
Outcomes of vitreoretinal surgery in patients with X-linked retinoschisis
, 1998 To assess the outcomes of vitreoretinal surgery in the treatment of vision-threatening posterior segment complications of X-linked retinoschisis. The authors performed a retrospective analysis of 16 eyes from 11 patients who underwent vitreoretinal ...
McDonald, H R +7 more
core +3 more sources