Results 101 to 110 of about 7,388,950 (300)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
X-ray spectroscopy of accreting black holes
, 2014 Measuring black hole spin has become a key topic in astrophysics, and recent focus on the spin powering of jets in X-ray binaries has heightened the need for accurate measurements of spin.
Plant, Daniel
core +1 more source
Ultrafast heat transfer in single palladium nanocrystals seen with an X-ray free-electron laser
Communications MaterialsWe report transient highly strained structural states in individual palladium (Pd) nanocrystals, electronically heated using an optical laser, which precede their uniform thermal expansion.
David Yang +13 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
X-ray observations of ultraluminous X-ray sources [PDF]
Astrophysics and Space Science, 2007 Invited talk at the 5th Stromlo Symposium. 10 pages, 4 figures.
openaire +4 more sources
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Automated detection of bone splinters in DEXA phantoms using deep neural networks
Current Directions in Biomedical Engineering, 2019 Dual energy radiographic imaging is a method to provide material information and can be used to differentiate between various tissue types. Dual energy X-ray absorption (DEXA) can be applied for breast density, osteoporosis or bone fracture analysis.
Rüger Steffen +5 more
doaj +1 more source
, 2015 Titanium oxide grafted on to the surfaces of chromatographic silica was investigated by x-ray fluorescence (XRF) and x-ray absorption (XAS) spectroscopy and the latter used before and after the extensive use of this material as a support for reversed ...
Collins, CH +3 more
core +1 more source
3D ultrastructural organization of whole Chlamydomonas reinhardtii cells studied by nanoscale soft x-ray tomography [PDF]
, 2012 The complex architecture of their structural elements and compartments is a hallmark of eukaryotic cells. The creation of high resolution models of whole cells has been limited by the relatively low resolution of conventional light microscopes and the ...
Achilleas S. Frangakis +32 more
core +2 more sources