Results 121 to 130 of about 7,388,950 (300)

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Preliminary Assessment of Quantitative Phase Analysis from Focal Construct Tomography

NDT - Journal of Non-Destructive Testing
New methods for real-time materials phase identification based upon focal construct tomography (FCT) have been examined. Such quantitative assessment has significant potential in sectors where in-line analysis is required, including screening within ...
Varsha Samuel, Daniel Spence, Liam Farmer, Simon Godber, Keith Rogers, Anthony Dicken   +5 more
doaj   +1 more source

View synthesis for kinetic depth X-ray imaging [PDF]

, 2012
This thesis reports the development and analysis of feature based synthesis of transmission X-ray images. The synthetic imagery is formed through matching and morphing or warping line-scan format images produced by a novel multi-view X-ray machine.
Abusaeeda, OA
core  

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Condensed tables for x-ray fluorescence analysis. [PDF]

, 1966
Condensed tables of 20 angles are provided which are simpler to use for many applications than the comprehensive tables already ...
Whittem, RN, Brockman, RH
core  

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Magnetic X-ray Reflectivity [PDF]

, 2001
The scope of the thesis is to demonstrate the feasibility to examine magnetization profiles of thin films and multilayer systems via magnetic soft and hard x-ray reflectivity.
Lott, Dieter
core   +1 more source

A pipeline for megahertz X-ray photon correlation spectroscopy on soft matter samples at the MID instrument of European XFEL

Journal of Synchrotron Radiation
In this article, we present the experimental protocol and data-processing framework for megahertz X-ray Photon Correlation Spectroscopy (MHz-XPCS) experiments on soft matter samples implemented at the Materials Imaging and Dynamics (MID) instrument of ...
Aliaksandr Leonau, Felix Brausse, James Wrigley, Mads B. Jakobsen, Trey Guest, Amir Tosson, Michelle Dargasz, Nimmi Das Anthuparambil, Felix Lehmkühler, Anita Girelli, Maddalena Bin, Fivos Perakis, Sebastian Retzbach, Fajun Zhang, Frank Schreiber, Matheus Teodoro, Cammille Carinan, Robert Rosca, Fabio Dall'Antonia, Wonhyuk Jo, Ulrike Boesenberg, Angel Rodriguez-Fernandez, Roman Shayduk, Jörg Hallmann, Alexey Zozulya, Jan-Etienne Pudell, Carsten Deiter, Luca Gelisio, Johannes Möller, Anders Madsen, Christian Gutt   +30 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source