Results 221 to 230 of about 6,416,221 (303)

Lithium‐Doped Hydroxyapatite Nanowires Rejuvenate Senescent Macrophages Via the Lysosome‐Dependent Ferroptosis Axis to Promote Aged Bone Regeneration

Advanced Science, EarlyView.
Li‐nHAP+GelMA promotes mandibular bone regeneration in aged mice by remodeling the senescent immune microenvironment. Local delivery of Li‐nHAP restores lysosomal homeostasis in senescent macrophages, reduces intracellular labile Fe2+ accumulation, ROS production, and lipid peroxidation, thereby suppressing macrophage ferroptosis and senescence ...
Baixi Chen, Ziduan Ding, Ruomei Li, Cheng Zhu, Zhiyu Zhu, Zitong Yang, Luyao Qu, Jin Hao, Lunguo Xia, Bing Fang, Lu Liu   +10 more
wiley   +1 more source

Electrode-omics reveals epochs in silicon anode evolution underpinning electrochemomechanical resilience. [PDF]

Sci Adv
Ko Y, Kim DM, Musgrove AL, Cha H, Klivansky L, Coyle J, Dopilka A, Trask SE, Rodrigues MF, Byeon YW, Kim H, Kostecki R, Veith GM, Helms BA.   +13 more
europepmc   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

A core-level electron spectroscopy study of gas-phase 1,2,3-benzotriazole and methyl derivatives. [PDF]

Beilstein J Nanotechnol
Bölke S, Nicolas C, Bozek J, Peisert H, Batchelor DR.   +4 more
europepmc   +1 more source

Cascade Desolvation and Conversion Reaction Driven by Self‐Tandem Catalysis for Wide‐Temperature Li‐S Batteries

Advanced Science, EarlyView.
A self‐tandem catalysis accelerating cascade reaction strategy is pioneered through constructing electron‐adjustable atom‐level Ce as the self‐tandem catalyst to lower energy barriers for fast Li+ desolvation and sequential sulfur conversion kinetics. The catalyzed cells operate effectively over a wide‐temperature range from 0 to ‐30 °C, delivering a ...
Jing Zhang, Shikai Yin, Mannan Yang, Hui Li, Caiyin You, Na Tian, Zhenjiang Cao, Yongzheng Zhang, Ruixian Duan, Hongzhen Lin, Jian Wang   +10 more
wiley   +1 more source

Asthma and corticosteroids "<i>odi et amo":</i> how to deal with it? [PDF]

Front Allergy
Borsari L, Carbonieri L, Verdini LM, Ruggieri V, Beghe' B.   +4 more
europepmc   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu, Sheng‐Jie Chang, Xiao‐Wei Liu, Shu‐Bao Zhang, Ying‐Jie Wang, Shan‐Jin Wang   +5 more
wiley   +1 more source

Synaptic high-frequency jumping synchronises vision to high-speed behaviour. [PDF]

Nat Commun
Mansour N, Takalo J, Kemppainen J, Bridges AD, MaBouDi H, Asgar Bohra A, Anielska K, Vasas V, Robert T, Yi Bu B, Shukla S, Zhou Y, Kittelmann M, Ouwendijk J, Mantell J, Lawson M, de Polavieja G, Duke E, Lazar AA, Verkade P, Chittka L, Juusola M.   +21 more
europepmc   +1 more source

Determining the Relationship Between Composition, Structure, and Device Properties of GexSe1‐x‐Based Selector‐Only Memory

Advanced Electronic Materials, EarlyView.
Composition‐dependent structural evolution in GeXSe1‐X selector‐only memory (SOM) is correlated with device switching behavior. Increasing Ge strengthens network rigidity, suppresses atomic motion, and stabilizes threshold switching, while narrowing the memory window. The revealed structure–property relationship provides a guideline for compositionally
Tien Anh Nguyen, Changdeok Han, Dipannita Ghosh, Suyong Chae, Moongyu Choi, Sanghyun Ban, Myoungsub Kim, Sangmin Yoo, Seung Hwan Lee, Sieun Chae   +9 more
wiley   +1 more source

Snapshots of internal protein crystal architecture at the nanoscale. [PDF]

Biophys J
Nia SS, Saha A, Cho J, Zhou ZH, Ercius P, Mecklenburg M.   +5 more
europepmc   +1 more source