Results 211 to 220 of about 6,416,221 (303)

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

open access: yesAdvanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao   +7 more
wiley   +1 more source

Landscape and evolutionary trends of nanotechnology in cancer radiosensitization. [PDF]

open access: yesDiscov Nano
Yan M   +6 more
europepmc   +1 more source

Therapeutic Peptide‐Programmed Liquid‐Crystalline Topology Switching for pH‐Gated Postoperative Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan   +12 more
wiley   +1 more source

Hybrid Semi‐Transparent Perovskite‐Photovoltaics and Concentrated Solar‐Thermal Harvesting Collectors

open access: yesAdvanced Science, EarlyView.
A hybrid semi‐transparent perovskite‐photovoltaic and concentrating solar‐thermal collector is developed to spectrally split sunlight for simultaneous electricity and heat generation. The design achieves thermal decoupling between the photovoltaic and thermal components, offering a promising route for efficient co‐harvesting of solar electricity and ...
Nada. A. Alati   +8 more
wiley   +1 more source

Multispacecraft Observations of the 2024 September 9 Backside Solar Eruption That Resulted in a Sustained Gamma Ray Emission Event. [PDF]

open access: yesSol Phys
Gopalswamy N   +8 more
europepmc   +1 more source

Spatiotemporally Precise Rheumatoid Arthritis Therapy via a Triple‐Locked Cascaded Nanoplatform With Dual‐Channel Self‐Reporting

open access: yesAdvanced Science, EarlyView.
An orthogonally programmable nanotheranostic (MB@YW NPs) enables precision therapy for rheumatoid arthritis. A triple‐locked (pH, HOCl/ONOO−, light) independently drives the release of methotrexate and sulfasalazine. Trackable by dual‐channel fluorescence, this coordinated drug delivery remodels the inflammatory microenvironment to markedly suppress ...
Jihong Liu   +11 more
wiley   +1 more source

Multifunctional Vertical Bulk‐Heterojunction Transistors With Amorphous GaOx for Neuromorphic Perception‐to‐Decision

open access: yesAdvanced Science, EarlyView.
A multifunctional vertical bulk‐heterojunction transistor (MVBT) with amorphous GaOx integrates four functionalities within a single neuromorphic device. Gate‐source operation enables 254 nm deep‐ultraviolet sensing and threshold neuronal firing, whereas three‐terminal operation supports broadband UV–vis‐NIR synaptic functions and bias‐controlled ...
Jinkui Si   +12 more
wiley   +1 more source

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