Results 61 to 70 of about 6,293,690 (277)

The effect of proton damage on the X-ray spectral response of MOS CCDs for the swift X-ray telescope [PDF]

open access: yes, 2002
The effect of non-ionising energy loss(NIEL) of protons in charge-coupled devices is to displace silicon atoms and any dopant materials present from their lattice positions to form lattice defects which in turn can trap electrons [1].
Abbey, AF   +9 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Towards scalable high-resolution x-ray imaging with direct-type perovskite detectors

open access: yesMaterials Futures
X-ray imaging plays a vital role in diverse fields, including medical diagnosis, industrial nondestructive testing, and security inspection. However, conventional x-ray detectors based on CdZnTe, CdTe, and a-Se suffer from inherent drawbacks such as low ...
Jiaming Li   +15 more
doaj   +1 more source

Highly sensitive diamond X-ray detector array for high-temperature applications

open access: yesChip
Diamond is a highly suitable material for X-ray detectors that can function effectively in harsh environments due to its unique properties such as ultrawide bandgap, high radiation resistance, excellent carrier mobility as well as remarkable chemical and
Wenjie Dou   +10 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Realizing nearly-zero dark current and ultrahigh signal-to-noise ratio perovskite X-ray detector and image array by dark-current-shunting strategy

open access: yesNature Communications, 2023
Although perovskite X-ray detectors have revealed promising properties, their dark currents are usually hundreds of times larger than the practical requirements.
Peng Jin   +13 more
doaj   +1 more source

View synthesis for depth from motion 3D x-ray imaging. [PDF]

open access: yes, 2009
The depth from motion or kinetic depth X-ray imaging (KDEX) technique is designed to enhance the luggage screening at airport checkpoints. The technique requires multiple views of the luggage to be obtained from an arrangement of linear X-ray detector ...
Liu, Y
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

X-ray calibration facility for plasma diagnostics of the MégaJoule laser

open access: yesEPJ Web of Conferences, 2013
The Laser MégaJoule (LMJ) located at CEA-CESTA will be equipped with x-ray plasma diagnostics using different kinds of x-ray components such as filters, mirrors, crystals, detectors and cameras.
Hubert S., Prévot V.
doaj   +1 more source

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