Results 61 to 70 of about 2,479,356 (392)

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Relativistic calculations of the x-ray emission following the Xe-Bi$^{83+}$ collision [PDF]

, 2014
We study the x-ray emission following the collision of a Bi$^{83+}$ ion with a neutral Xe atom at the projectile energy 70 MeV/u. The collisional and post-collisional processes are treated separately.
Gumberidze, A., Hagmann, S., Kozhedub, Y. S., Plunien, G., Shabaev, V. M., Stöhlker, Th., Tupitsyn, I. I.   +6 more
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

The origin and chronology of medieval silver coins based on the analysis of chemical composition

Nukleonika, 2015
Medieval Central Europe coins - the Saxon coins, also called as the Otto and Adelheid denarii, as well as the Polish ones, the Władysław Herman and Bolesław Śmiały coins - were examined to determine their provenance and dating.
Pańczyk Ewa, Sartowska Bożena, Waliś Lech, Dudek Jakub, Weker Władysław, Widawski Maciej   +5 more
doaj   +1 more source

Laboratory-Based Correlative Soft X-ray and Fluorescence Microscopy in an Integrated Setup [PDF]

, 2023
Julius Reinhard, Sophia Kaleta, Johann J. Abel, Felix Wiesner, Martin Wünsche, Eric Seemann, Martin Westermann, Thomas Weber, Jan Nathanael, Alexander Iliou, Henryk Fiedorowicz, Falk Hillmann, Christian Eggeling, G. G. Paulus, Silvio Fuchs   +14 more
openalex   +1 more source

Portable X-ray fluorescence (pXRF) applications in tropical Soil Science

, 2017
The X-ray fluorescence (XRF) is an analytical technique for determination of elemental composition of different materials. In soils, the XRF has many pedological, environmental and agronomic applications, mainly after the emergence of portable equipments
B. Ribeiro, S. H. Silva, Elen Alvarenga Silva, L. Guilherme   +3 more
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Experimental Demonstration of X-Ray Fluorescence CT Using a Spatially Distributed Multi-Beam X-Ray Source

Frontiers in Physics, 2020
X-ray fluorescence computed tomography (XFCT) is a high-sensitivity imaging modality for high-atomic elements such as gadolinium (Gd) or gold (Au). In order to improve the contrast of x-ray fluorescence (XRF) signals in the raw projection data, common ...
Zhiqiang Chen, Zhiqiang Chen, Siyuan Zhang, Siyuan Zhang, Liang Li, Liang Li   +5 more
doaj   +1 more source

Holographic analysis of diffraction structure factors

, 2002
We combine the theory of inside-source/inside-detector x-ray fluorescence holography and Kossel lines/x ray standing waves in kinematic approximation to directly obtain the phases of the diffraction structure factors.
B. Adams, B.W. Batterman, C. S. Fadley, D. K. Shuh, D. Sayre, I. A. Vartanyants, J. J. Bucher, J.A. Golovchenko, J.J. Bucher, J.M. Cowley, L. Fabris, M. A. Van Hove, M. J. Press, M. Kopecky, M. Kopecky, M. Tegze, M. Tegze, M. W. West, N. Mannella, P.M. Len, S. Marchesini, S. Marchesini, S. Marchesini, T. Gog, T. Gog, T. Hiort, W. C. Stolte, W. Shen, Z. Hussain   +28 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source