Results 61 to 70 of about 7,088,795 (306)

Research on X-ray Fluorescence Enhanced Fluoroscopy Imaging Technology

Photonics, 2021
Chest X-ray fluoroscopy is a commonly used medical imaging method, which has a wide range of applications in the diagnosis of lung diseases and other fields.
Zhenyao Yan, Liang Li, Rui Qiu, Zhiqiang Chen   +3 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

A Multi-Analytical Approach for the Investigation of Black Crusts on Two Monuments in Athens, Greece

Heritage
Analytical studies of archeological materials often face challenges, such as the merging of heterogeneous, multidimensional datasets from complementary analytical techniques, and incorporating site- and user-defined parameters.
Dimitrios Mitsos, Eleni Palamara, Andreas Germanos Karydas, Evangelos Gerasopoulos, Vasilis Poulopoulos   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Western oceanus procellarum as seen by c1xs on chandrayaan-1 [PDF]

, 2014
We present the analysis of an X-ray fluorescence (XRF) observation of the western part of Oceanus Procellarum on the Moon’s nearside made by the Chandrayaan-1 X-ray Spectrometer on 10th February 2009.
Crawford I, Joy, K. H., Crawford, I. A., Joy, K.H., Swinyard, B.M., Howe C, Weider, S.Z., Swinyard B, Kellett, B.J., Weider S, Swinyard, B. M., Howe, C. J., Howe, C.J., Joy K, Kellett B, Kellett, B. J., Weider, S. Z., Crawford, Ian   +17 more
core   +1 more source

X-Ray Fluorescence Experiments with Polarized X Rays [PDF]

Advances in X-ray Analysis, 1974
AbstractTwo methods of obtaining polarized x-rays for fluorescence experiments are discussed. Compton scattering from a low-Z scatterer is the usual method used in such experiments. The polarization of x-rays undergoing anomalous Borrmann transmission in a dislocation-free crystal is also described and preliminary results are presented.
Howell, R.H., Pickles, W.L., Cate, J.L. Jr.   +2 more
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

X-ray fluorescence microscopy of olfactory receptor neurons

, 2009
We report a x-ray fluorescence microscopy study of cells and tissues from the olfactory system of Xenopus laevis. In this experiment we focus on sample preparation and experimental issues, and present first results of fluorescence maps of the elemental ...
Herbst, J., T Salditt, ; 1Institute for X-ray Physics, Georg-August-University, Friedrich-Hund-Pl. 1, 37077 Göttingen, Germany, J Herbst, ; 1Institute for X-ray Physics, Georg-August-University, Friedrich-Hund-Pl. 1, 37077 Göttingen, Germany, Breunig, E., D Schild, ; 2Department of Molecular Neurophysiology, Georg-August University Göttingen, Germany, T Dučić, ; 1Institute for X-ray Physics, Georg-August-University, Friedrich-Hund-Pl. 1, 37077 Göttingen, Germany, Salditt, Tim, E Breunig, ; 2Department of Molecular Neurophysiology, Georg-August University Göttingen, Germany, Dučić, T., Nováková, E., Susini, J., E Nováková, ; 1Institute for X-ray Physics, Georg-August-University, Friedrich-Hund-Pl. 1, 37077 Göttingen, Germany, R Tucoulu, ; 3European Synchrotron Radiation Facility ESRF, 6 rue Jules Horowitz, 38043 Grenoble, France, Schild, D., J Susini, ; 3European Synchrotron Radiation Facility ESRF, 6 rue Jules Horowitz, 38043 Grenoble, France, Tucoulu, R., R Tucoulu, J Susini, E Nováková, E Breunig, T Salditt, T Dučić, D Schild, J Herbst   +23 more
core   +1 more source

Correlative single-cell hard X-ray computed tomography and X-ray fluorescence imaging

Communications Biology
X-ray computed tomography (XCT) and X-ray fluorescence (XRF) imaging are two non-invasive imaging techniques to study cellular structures and chemical element distributions, respectively.
Zihan Lin, Xiao Zhang, Purbasha Nandi, Yuewei Lin, Liguo Wang, Yong S. Chu, Timothy Paape, Yang Yang, Xianghui Xiao, Qun Liu   +9 more
doaj   +1 more source