Results 41 to 50 of about 1,009,330 (345)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Extending Imaging Volume in Soft X‐Ray Tomography
Advanced Photonics Research, 2023 Soft X‐ray tomography offers rapid imaging of whole, single cells with a few tens of nanometers spatial resolution without fixation or labeling. Herein, this technique is limited to specimens about 10 μm thick, such that applications of soft X‐ray ...
Axel Ekman +6 more
doaj +1 more source
Healing X-ray scattering images [PDF]
IUCrJ, 2017 X-ray scattering images contain numerous gaps and defects arising from detector limitations and experimental configuration. We present a method to heal X-ray scattering images, filling gaps in the data and removing defects in a physically meaningful manner.
Jiliang Liu +5 more
openaire +4 more sources
, 2012 State of the art X-ray imaging sensors comprise a trade-off between the achievable efficiency and the spatial resolution. To overcome such limitations, the use of structured and scintillator filled aluminum oxide (AlOx) matrices has been investigated. We
F Sukowski +7 more
core +1 more source
X-ray high-resolution diffraction using refractive lenses [PDF]
, 2005 Refractive x-ray lenses have recently been applied for imaging and scanning microscopy with hard x rays. We report the application of refractive lenses in an optical scheme for high-resolution x-ray diffraction, performed at a high brilliance synchrotron
Drakopoulos, Michael +3 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
X ray imaging goes digital [PDF]
BMJ, 2006 Digital x ray imaging has brought obvious benefits to health care, but, as with all new technologies, it both requires and leads to changes in behaviour and processes, some obvious and some less so. The issues include cost and productivity, the need to acquire new skills, radiation doses, overuse, and image quality.
Kwan-Hoong, Ng, Madan M, Rehani
openaire +2 more sources
Quantitative Imaging of Single, Unstained Viruses with Coherent X-rays
, 2008 Since Perutz, Kendrew and colleagues unveiled the structure of hemoglobin and myoglobin based on X-ray diffraction analysis in the 1950s, X-ray crystallography has become the primary methodology used to determine the 3D structure of macromolecules ...
A. C. Steven +11 more
core +1 more source
Novel X-ray imaging technology enables significant patient dose reduction in interventional cardiology while maintaining diagnostic image quality [PDF]
, 2015 Objectives: The purpose of this study was to quantify the reduction in patient radiation dose during coronary angiography (CA) by a new X-ray technology, and to assess its impact on diagnostic image quality.
Bacher, Klaus +9 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source