Results 51 to 60 of about 8,029,441 (299)

Towards time-resolved multiscale and multimodal imaging

npj Imaging
Current biomedical imaging focuses on spatial detail but overlooks time, limiting our understanding of disease progression. There is an unmet need for temporal atlases that align multiscale and multimodal data across defined timepoints, enabling dynamic ...
Jishizhan Chen
doaj   +1 more source

Alpha shapes: determining 3D shape complexity across morphologically diverse structures

BMC Evolutionary Biology, 2018
Background Following recent advances in bioimaging, high-resolution 3D models of biological structures are now generated rapidly and at low-cost. To use this data to address evolutionary and ecological questions, an array of tools has been developed to ...
James D. Gardiner, Julia Behnsen, Charlotte A. Brassey   +2 more
doaj   +1 more source

Nano Organic Co‐Crystal Scintillator for X‐ray Imaging

Small Structures, 2023
Traditional‐metal‐containing scintillators are widely used in X‐ray imaging due to their efficient X‐ray absorption and output of visible light. However, they suffer from heavy‐metal toxicity, environmental stability, harsh preparation, and afterglow ...
Qisheng Sun, Hongyun Wang, Jing Li, Fei Li, Weigang Zhu, Xiaotao Zhang, Qiushui Chen, Huanghao Yang, Wenping Hu   +8 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Registration and tracking to integrate X-ray and MR images in an XMR facility [PDF]

, 2003
We describe a registration and tracking technique to integrate cardiac X-ray images and cardiac magnetic resonance (MR) images acquired from a combined X-ray and MR interventional suite (XMR).
Rueckert, D, Hipwell, J, Hegde, S, Hill, D L G, Hill, DL, Razavi, R; id_orcid, Edwards, PJ, Sanchez-Ortiz, G, Rhode, KS, Sanchez Ortiz, G, Edwards, P J, Rhode, K S; id_orcid, Rahunathan, V, Razavi, R   +13 more
core   +1 more source

X-ray phase-contrast computed tomography for full-breast mastectomy imaging at the Australian Synchrotron

, 2021
One of the imaging modalities offered by the Imaging and Medical Beamline (IMBL) at the Australian Synchrotron is Xray phase-contrast propagation-based computed tomography (PB-CT). The unique combination of high coherence and high brightness of radiation
Stevenson, Andrew W., Dimmock, Matthew, Hasermann, Daniel, Maksimenko, Anton, Lewis, Sarah (R21243), Nesterets, Yakov I., Taba, Seyedamir T., Quiney, Harry M., Hall, Christopher J., Thompson, Darren, Mayo, Sheridan C., Arhatari, Benedicta D., Brennan , Patrick C., Gureyev, Timur E.   +13 more
core   +1 more source

Two-view topogram-based anatomy-guided CT reconstruction for prospective risk minimization

Scientific Reports
To facilitate a prospective estimation of the effective dose of an CT scan prior to the actual scanning in order to use sophisticated patient risk minimizing methods, a prospective spatial dose estimation and the known anatomical structures are required.
Chang Liu, Laura Klein, Yixing Huang, Edith Baader, Michael Lell, Marc Kachelrieß, Andreas Maier   +6 more
doaj   +1 more source

Polymer composite microtube array produced by meniscus-guided approach

AIP Advances, 2013
Single freestanding microtubes of poly(methyl methacrylate)/polypyrrole (PMMA/PPy) are produced based on a meniscus-guided approach. A ring-deposit of nanoparticles is first formed in a meniscus solution of PMMA/PPy nanoparticles by outward liquid flow ...
Kyu Hwang Won, Byung Mook Weon, Jung Ho Je   +2 more
doaj   +1 more source

Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation

IEEE Journal of Translational Engineering in Health and Medicine, 2014
Real-time imaging is required to guide minimally invasive catheter-based cardiac interventions. While transesophageal echocardiography allows for high-quality visualization of cardiac anatomy, X-ray fluoroscopy provides excellent visualization of devices.
Aruna V. Arujuna, R. James Housden, Yingliang Ma, Ronak Rajani, Gang Gao, Niels Nijhof, Pascal Cathier, Roland Bullens, Geert Gijsbers, Victoria Parish, Stamatis Kapetanakis, Jane Hancock, C. Aldo Rinaldi, Michael Cooklin, Jaswinder Gill, Martyn Thomas, Mark D. O'neill, Reza Razavi, Kawal S. Rhode   +18 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source