Results 71 to 80 of about 525,920 (315)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

VELOCITY MEASUREMENTS IN CAVITATING FLOWS USING FAST X-RAY IMAGING [PDF]

, 2013
A promising method to measure velocity fields in complex two-phase flows such us cavitating flows is presented. Dynamics of the liquid phase and the bubbles are both investigated.
KHLIFA, Ilyass, VABRE, Alexandre, HOCEVAR, Marko, FUZIER, Sylvie, FEZZAA, Kamel, COUTIER-DELGOSHA, Olivier   +5 more
core  

Two-view topogram-based anatomy-guided CT reconstruction for prospective risk minimization

Scientific Reports
To facilitate a prospective estimation of the effective dose of an CT scan prior to the actual scanning in order to use sophisticated patient risk minimizing methods, a prospective spatial dose estimation and the known anatomical structures are required.
Chang Liu, Laura Klein, Yixing Huang, Edith Baader, Michael Lell, Marc Kachelrieß, Andreas Maier   +6 more
doaj   +1 more source

Polymer composite microtube array produced by meniscus-guided approach

AIP Advances, 2013
Single freestanding microtubes of poly(methyl methacrylate)/polypyrrole (PMMA/PPy) are produced based on a meniscus-guided approach. A ring-deposit of nanoparticles is first formed in a meniscus solution of PMMA/PPy nanoparticles by outward liquid flow ...
Kyu Hwang Won, Byung Mook Weon, Jung Ho Je   +2 more
doaj   +1 more source

Novel System for Real-Time Integration of 3-D Echocardiography and Fluoroscopy for Image-Guided Cardiac Interventions: Preclinical Validation and Clinical Feasibility Evaluation

IEEE Journal of Translational Engineering in Health and Medicine, 2014
Real-time imaging is required to guide minimally invasive catheter-based cardiac interventions. While transesophageal echocardiography allows for high-quality visualization of cardiac anatomy, X-ray fluoroscopy provides excellent visualization of devices.
Aruna V. Arujuna, R. James Housden, Yingliang Ma, Ronak Rajani, Gang Gao, Niels Nijhof, Pascal Cathier, Roland Bullens, Geert Gijsbers, Victoria Parish, Stamatis Kapetanakis, Jane Hancock, C. Aldo Rinaldi, Michael Cooklin, Jaswinder Gill, Martyn Thomas, Mark D. O'neill, Reza Razavi, Kawal S. Rhode   +18 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Locating regions of interest prior to X-ray imaging using stereo-photogrammetry [PDF]

, 2011
The research project aims at locating regions of interest (ROIs) on human subjects prior to X-ray imaging on the Lodox Statscan whole body imaging ...
Kulkarni, Radhika
core  

Using small-angle X-ray scattering to investigate the compaction behaviour of a granulated clay [PDF]

, 2015
The compaction behaviour of a commercial granulated clay (magnesium aluminium smectite, gMgSm) was investigated using macroscopic pressure-density measurements, X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray microtomography (XμT) and ...
Conway, Barbara R, Sweeney, Francis, Laity, Peter R., Asare-Addo, Kofi, Šupuk, Enes, Conway, Barbara R.   +5 more
core   +1 more source

Coherent X-rays reveal anomalous molecular diffusion and cage effects in crowded protein solutions

Nature Communications
Understanding protein motion within the cell is crucial for predicting reaction rates and macromolecular transport in the cytoplasm. A key question is how crowded environments affect protein dynamics through hydrodynamic and direct interactions at ...
Anita Girelli, Maddalena Bin, Mariia Filianina, Michelle Dargasz, Nimmi Das Anthuparambil, Johannes Möller, Alexey Zozulya, Iason Andronis, Sonja Timmermann, Sharon Berkowicz, Sebastian Retzbach, Mario Reiser, Agha Mohammad Raza, Marvin Kowalski, Mohammad Sayed Akhundzadeh, Jenny Schrage, Chang Hee Woo, Maximilian D. Senft, Lara Franziska Reichart, Aliaksandr Leonau, Prabhu Rajaiah Prince, William Chèvremont, Tilo Seydel, Jörg Hallmann, Angel Rodriguez-Fernandez, Jan-Etienne Pudell, Felix Brausse, Ulrike Boesenberg, James Wrigley, Mohamed Youssef, Wei Lu, Wonhyuk Jo, Roman Shayduk, Trey Guest, Anders Madsen, Felix Lehmkühler, Michael Paulus, Fajun Zhang, Frank Schreiber, Christian Gutt, Fivos Perakis   +40 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source