Results 61 to 70 of about 6,239 (205)

Mapping Nanoscale Protein‐Corona Kinetics of DoE‐Optimized Perfluorocarbon Encapsulated‐PLGA Nanoparticles by In Situ, Time‐Resolved Synchrotron SAXS

Advanced Healthcare Materials, EarlyView.
A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.
Joice Maria Joseph, Maria Rosa Gigliobianco, Cristina Minnelli, Paolo Moretti, Francesco Spinozzi, Giovanna Mobbili, Sara Pistolesi, Cristina Casadidio, Gabriella Teti, Roberta Censi, Stefano Antonio Gattone, Piera Di Martino   +11 more
wiley   +1 more source

Spatial properties of $\pi-\pi$ conjugated network in semicrystalline polymer thin films studied by intensity x-ray cross-correlation functions

, 2013
We present results of x-ray study of spatial properties of $\pi-\pi$ conjugated networks in polymer thin films. We applied the x-ray cross-correlation analysis to x-ray scattering data from blends of poly(3-hexylthiophene) (P3HT) and gold nanoparticles ...
Fratoddi, I., Gorobtsov, O. Y., Grigorian, S., Grodd, L., Kurta, R. P., Mikayelyan, E., Sprung, M., Vartanyants, I. A., Venditti, I.   +8 more
core   +1 more source

RNA quantification using gold nanoprobes - application to cancer diagnostics [PDF]

, 2010
Molecular nanodiagnostics applied to cancer may provide rapid and sensitive detection of cancer related molecular alterations, which would enable early detection even when those alterations occur only in a small percentage of cells.
Joao Conde, Jesus M de la Fuente, Pedro V Baptista   +2 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Clickable X-ray Nanoprobes for Nanoscopic Bioimaging of Cellular Structures

JACS Au
Synchrotron-based X-ray microscopy (XRM) has garnered widespread attention from researchers due to its high spatial resolution and excellent energy (element) resolution. Existing molecular probes suitable for XRM include immune probes and genetic labeling probes, enabling the precise imaging of various biological targets within cells.
Qiaowei Tang, Dapeng Yin, Yubo Liu, Jichao Zhang, Yong Guan, Huating Kong, Yiliu Wang, Xiangzhi Zhang, Jiang Li, Lihua Wang, Jun Hu, Xiaoqing Cai, Ying Zhu   +12 more
openaire   +3 more sources

Fluorescence imaging ofDictyostelium discoideumwith a hard X-ray nanoprobe

Journal of Physics: Conference Series, 2009
The preparation and a novel sample environment for X-ray based imaging of freeze-dried Dictyostelium discoideum cells are presented. As a first application a fluorescence imaging experiment with a nanofocused hard X-ray beam has been performed. The successful preparation was verified in elemental mappings with sub-200nm resolution, which allowed for ...
Tucoulou, R., Salditt, Tim, Giewekemeyer, K., Hantke, M., Beta, C., K Giewekemeyer, ; 1Institute for X-ray Physics, Georg-August-University, Friedrich-Hund-Pl. 1, 37077 Göttingen, Germany, M Hantke, ; 1Institute for X-ray Physics, Georg-August-University, Friedrich-Hund-Pl. 1, 37077 Göttingen, Germany, C Beta, ; 2Max-Planck-Insitute for Dynamics and Self-Organization, Am Faßberg 11, 37077 Göttingen, Germany, R Tucoulou, ; 4European Synchrotron Radiation Facility (ESRF), BP 220, 38043 Grenoble, France, T Salditt, ; 1Institute for X-ray Physics, Georg-August-University, Friedrich-Hund-Pl. 1, 37077 Göttingen, Germany   +9 more
openaire   +2 more sources

Synthesis of glutamine-based green emitting carbon quantum dots as a fluorescent nanoprobe for the determination of iron (Fe3+) in Solanum tuberrosum (potato)

Heliyon, 2023
Herein, we reported the use of N-doped green-emitting carbon quantum dots (N-CQDs) as a fluorescent probe for determining of Fe3+ ions in Solanum tuberosum for the first time.
Olanrewaju A. Aladesuyi, Oluwatobi S. Oluwafemi   +1 more
doaj   +1 more source

Structure and Dynamics of Metalloproteins in Live Cells [PDF]

, 2008
X-ray absorption spectroscopy (XAS) has emerged as one of the premier tools for investigating the structure and dynamic properties of metals in cells and in metal containing biomolecules. Utilizing the high flux and broad energy range of X-rays supplied
Cook, Jeremy D., Penner-Hahn, James E., Stemmler, Timothy L.   +2 more
core   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Design and performance of an X-ray scanning microscope at the Hard X-ray Nanoprobe beamline of NSLS-II [PDF]

Journal of Synchrotron Radiation, 2017
A hard X-ray scanning microscope installed at the Hard X-ray Nanoprobe beamline of the National Synchrotron Light Source II has been designed, constructed and commissioned. The microscope relies on a compact, high stiffness, low heat dissipation approach and utilizes two types of nanofocusing optics. It is capable of imaging with ∼15 nm × 15 nm spatial
E, Nazaretski, H, Yan, K, Lauer, N, Bouet, X, Huang, W, Xu, J, Zhou, D, Shu, Y, Hwu, Y S, Chu   +9 more
openaire   +2 more sources