Results 31 to 40 of about 1,181,189 (249)

A Chandra X-ray Study of the Globular Cluster M80

, 2003
We report our analysis of a Chandra X-ray observation of the rich globular cluster M80, in which we detect some 19 sources to a limiting 0.5-2.5 keV X-ray luminosity of 7*10^30 ergs/s within the half-mass radius.
Auwers G. F., Brocato E., C. O. Heinke, D. A. Lloyd, H. N. Cohn, Hakala P. J., J. E. Grindlay, Johnston H. M., P. D. Edmonds, P. M. Lugger, Predehl P., S. S. Murray, Verbunt F.   +12 more
core   +1 more source

Faint X-ray Sources in the Globular Cluster Terzan 5 [PDF]

, 2006
We report our analysis of a Chandra X-ray observation of the rich globular cluster Terzan 5, in which we detect 50 sources to a limiting 1.0-6 keV X-ray luminosity of 3*10^{31} ergs/s within the half-mass radius of the cluster. Thirty-three of these have
C. O. Heinke, D. Pooley, H. N. Cohn, J. E. Grindlay, Johnston H. M., P. M. Lugger, R. Wijnands, W. H. G. Lewin   +7 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The Chandra Source Catalog [PDF]

, 2009
The Chandra Source Catalog (CSC) is a general purpose virtual X-ray astrophysics facility that provides access to a carefully selected set of generally useful quantities for individual X-ray sources, and is designed to satisfy the needs of a broad-based ...
Anderson, Craig S., Bonaventura, Nina R., Chen, Judy C., Davis, John E., Doe, Stephen M., Evans, Ian N., Evans, Janet D., Fabbiano, Giuseppina, Galle, Elizabeth C., Gibbs II, Danny G., Glotfelty, Kenny J., Grier, John D., Hain, Roger M., Hall, Diane M., Harbo, Peter N., He, Houck, John C., Karovska, Margarita, Kashyap, Vinay L., Lauer, Jennifer, McCollough, Michael L., McDowell, Jonathan C., Miller, Joseph B., Mitschang, Arik W., Morgan, Douglas L., Mossman, Amy E., Nichols, Joy S., Nowak, Michael A., Plummer, David A., Primini, Francis A., Refsdal, Brian L., Rots, Arnold H., Siemiginowska, Aneta, Sundheim, Beth A., Tibbetts, Michael S., Van Stone, David W., Winkelman, Sherry L., Xiangqun, Zografou, Panagoula   +38 more
core   +3 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

A systematic cross-search for radio/infrared counterparts of XMM-Newton sources

, 2010
We present a catalog of cross-correlated radio, infrared and X-ray sources using a very restrictive selection criteria with an IDL-based code developed by us.
A. Caccianiga, A. J. Muñoz-Arjonilla, A.D.P. Hands, A.J. Green, B.J. Boyle, C. Feruglio, E. Sánchez-Ayaso, F.J. Carrera, G. E. Romero, G. Fabbiano, G. Micela, G. Novara, I. Furenlid, J. A. Combi, J. Ebrero, J. F. Albacete Colombo, J. López-Santiago, J. López-Santiago, J. Martí, J. R. Sánchez-Sutil, J.J. Condon, J.R. Allington-Smith, L. Pellizza, M. Seldner, M.G. Watson, P. L. Luque-Escamilla, P. Severgnini, P.J.E. Peebles, P.M. Woodward, R. Della Ceca, R. Della Ceca, R.K. Smith, S. Mateos, S. Mateos, X. Barcons, X. Barcons   +35 more
core   +1 more source

The HELLAS2XMM survey: IV. Optical identifications and the evolution of the accretion luminosity in the Universe [PDF]

, 2003
We present results from the photometric and spectroscopic identification of 122 X-ray sources recently discovered by XMM-Newton in the 2-10 keV band (the HELLAS2XMM 1dF sample).
A. Baldi, A. Comastri, Akiyama, Alexander, Baldi, Banse, Barcons, Barger, Barger, Bertin, Brandt, Brusa, C. Vignali, Cavaliere, Comastri, Comastri, Comastri, Cowie, Della Ceca, Elvis, F. Cocchia, F. Fiore, F. La Franca, Fabian, Ferrarese, Fiore, Fiore, Fiore, Fontana, Franceschini, Franceschini, G. C. Perola, G. Matt, George, Giacconi, Giacconi, Giommi, Granato, Hartwick, Hasinger, Ho, La Franca, Laor, Lehmann, Lilly, M. Brusa, M. Mignoli, Madau, Madau, Mainieri, Menci, Mineo, Mushotzky, N. Carangelo, Oke, P. Ciliegi, P. Severgnini, R. Maiolino, S. Molendi, Schmidt, Schmidt, Setti, Ueda   +62 more
core   +5 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source