Results 51 to 60 of about 9,803,268 (311)

Ultraluminous X-ray Sources [PDF]

open access: yesProceedings of Accretion Processes in Cosmic Sources – II — PoS(APCS2018), 2019
Ultraluminous X-ray sources (ULXs) represent a class of binary systems that are more luminous than any black hole in our Galaxy. The nature of these objects remained unclear for a long time. The most popular models for the ULXs involve either intermediate mass black holes (IMBHs) or stellar-mass black holes accreting at super-Eddington rates.
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Hard-X-ray Photoelectron Spectroscopy of Atoms and Molecules

open access: yes, 2015
We review here the current status of atomic and molecular HAXPES, both experimentally and theoretically. After the era of the ESCA technique, atomic and molecular HAXPES experienced several decades when the emphasis in gas-phase research was in the soft ...
Maria Novella Piancastelli   +5 more
core   +1 more source

Polymorphism in a high-entropy alloy

open access: yesNature Communications, 2017
Whether a polymorphic transition exists in high entropy alloys or not remains unclear since discovery of these alloys more than a decade ago. Here authors report an irreversible polymorphic transition fromfcc to hcp in the prototype FeCoCrMnNi high ...
Fei Zhang   +12 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

TeV gamma-ray emission from accreting binary pulsars [PDF]

open access: yes, 1990
The high-mass X-ray binary SMC X-1 has been observed during the interval 1986-1989 at a threshold γ-ray energy of 0.4 TeV using the University of Durham Mark III air Cerenkov telescope at Narrabri.
Mannings, Vincent, Mannings, V
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

The Search For Pulsar Wind Nebulae in the Very High Energy Gamma-ray Regime [PDF]

open access: yes, 2010
The aim of this Thesis is to study the development of pulsar wind nebulae in the TeV regime and in doing so uncover more sources which have as yet not been observed at these wavelengths.
KEOGH, DOMINIC,ROBERT   +1 more
core  

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