Results 61 to 70 of about 9,379,945 (304)
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Hydrogen-triggered X-Ray Bursts from SAX J1808.4−3658? The Onset of Nuclear Burning
The Astrophysical Journal, 2023 We present a study of weak, thermonuclear X-ray bursts from the accreting millisecond X-ray pulsar SAX J1808.4−3658. We focus on a burst observed with the Neutron Star Interior Composition Explorer on 2019 August 9, and describe a similar burst observed ...
Sierra Casten +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
X-ray spectroscopy of accreting black holes
, 2014 Measuring black hole spin has become a key topic in astrophysics, and recent focus on the spin powering of jets in X-ray binaries has heightened the need for accurate measurements of spin.
Plant, Daniel
core +1 more source
ZnO Nanowire Cold Cathode Hemispherical X‐Ray Sources
Advanced Electronic MaterialsCurved or spherical X‐ray sources are significant for use in intraoperative radiotherapy, adaptive static medical imaging, and high‐throughput industrial inspection, but they are hard to achieve using traditional thermionic cathode point electron sources.
Zhipeng Zhang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
X-ray emission from faint galaxies and quasars [PDF]
, 1996 In this thesis a study of faint X-ray sources is undertaken to understand the nature and origin of the Cosmic X-ray Background (XRB). A study of the X-ray variability characteristics of the QSO population is also presented.
Almaini, Omar, Almaini, O
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A Comprehensive Comparison of Spin-up and Spin-down Episodes of 4U 1538-522 Observed with NuSTAR
The Astrophysical Journal4U 1538-522 is a persistent high-mass X-ray binary that exhibits secular spin evolution. In 2019, it underwent a torque reversal from spinning up to spinning down.
Yongfeng Hu, Long Ji, Cong Yu, Lili Yang
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
TeV gamma-ray emission from accreting binary pulsars [PDF]
, 1990 The high-mass X-ray binary SMC X-1 has been observed during the interval 1986-1989 at a threshold γ-ray energy of 0.4 TeV using the University of Durham Mark III air Cerenkov telescope at Narrabri.
Mannings, Vincent, Mannings, V
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