Results 91 to 100 of about 15,609 (265)

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

X-Ray Polarimetry of the Dipping Accreting Neutron Star 4U 1624–49

The Astrophysical Journal
We present the first X-ray polarimetric study of the dipping accreting neutron star 4U 1624−49 with the Imaging X-ray Polarimetry Explorer. We report a detection of polarization in the nondip time intervals with a confidence level of 99.99%.
M. Lynne Saade, Philip Kaaret, Andrea Gnarini, Juri Poutanen, Francesco Ursini, Stefano Bianchi, Anna Bobrikova, Fabio La Monaca, Alessandro Di Marco, Fiamma Capitanio, Alexandra Veledina, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien-Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Niccolò Di Lalla, Immacolata Donnarumma, Victor Doroshenko, Michal Dovčiak, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Javier A. García, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Henric Krawczynski, Luca Latronico, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Frédéric Marin, Andrea Marinucci, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Giorgio Matt, Ikuyuki Mitsuishi, Tsunefumi Mizuno, Fabio Muleri, Michela Negro, Chi-Yung Ng, Stephen L. O’Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Maura Pilia, Andrea Possenti, Simonetta Puccetti, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Paolo Soffitta, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Kinwah Wu, Fei Xie, Silvia Zane   +100 more
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Long Thermonuclear Burst–driven Thermal–Viscous Instability of Accretion Disk: Triggering an Outburst-like X-Ray Flare

The Astrophysical Journal
We report on NICER and MAXI observations of a long-duration thermonuclear X-ray burst and a subsequent outburst-like X-ray flare from the neutron star low-mass X-ray binary MAXI J0911–655. Prior to the burst, the source was in a persistent low/hard state
Wenhui Yu, Zhaosheng Li, Yuanyue Pan, Yanan Wang, Erlin Qiao   +4 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Photospheric Radius Expansion Thermonuclear Burst and X-Ray Reflection from the Neutron Star X-Ray Binary 4U 1702-429

The Astrophysical Journal
We perform a comprehensive study of thermonuclear bursts from the neutron star low-mass X-ray binary 4U 1702–429 detected with NICER and XMM-Newton. The thermonuclear burst detected with NICER shows clear evidence of a photospheric radius expansion (PRE)
Manoj Mandal, Sachindra Naik, Gaurava Kumar Jaisawal   +2 more
doaj   +1 more source

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Discovery of a New Phase-transient Cyclotron Line in A0535+26: Constraints on the Accretion Geometry

The Astrophysical Journal
In 2020 November, A0535+26 underwent one of its brightest outbursts, reaching nearly 12 Crab in X-ray flux. Observed by Insight-HXMT, NuSTAR, NICER, and AstroSat, this event provided valuable insights into Be/X-ray binaries.
Ashwin Devaraj, Biswajit Paul, Varun Bhalerao, Dipanjan Mukherjee   +3 more
doaj   +1 more source

Longitudinal Changes in Adiposity After a Youth Sport‐Related Knee Injury: Informing Posttraumatic Osteoarthritis Prevention

Arthritis Care &Research, EarlyView.
Objective Youth who experience a sport‐related knee injury have elevated odds of becoming overweight or developing obesity in 3 to 10 years, compounding their risk for posttraumatic osteoarthritis (PTOA). To inform prevention strategies, this study compared patterns of adiposity change between youth with a sport‐related knee injury and uninjured youth ...
Justin M. Losciale, Nuria E. J. Jansen, Christina Y. Le, Leo Lu, Hui Xie, Marienke van Middelkoop, Jackie L. Whittaker   +6 more
wiley   +1 more source

Estimating the Prevalence and Incidence of Symptomatic Hand Osteoarthritis in the Netherlands Using Primary Care Electronic Health Records

Arthritis Care &Research, EarlyView.
Objective Estimating the incidence and prevalence of symptomatic hand osteoarthritis (OA) in the Dutch population using a validated algorithm that integrates free‐text data from primary care electronic health records (EHRs). Methods This retrospective cohort study used the Integrated Primary Care Information database, including EHRs from approximately ...
Onur Kaya, Jacoline van den Driest, Laura Struik, Margreet Kloppenburg, Ruud Selles, Daniel Prieto Alhambra, Sita Bierma‐Zeinstra, Dieuwke Schiphof   +7 more
wiley   +1 more source