Results 91 to 100 of about 140,451 (265)

Thermodynamics of Deoxidization of Pipeline Steel Based on Technology of Oxide Metallurgy

open access: yesTeshugang, 2007
The optimum conditions of molten steel to precipitate Ti2O3inclusion in solid-liquid dual phase region during solidification are obtained by study on thermodynamics of deoxidization of pipeline steel X100 (0. 03 ~0. 05C, 1.70 ~ 1. 90Mn, 0. 15 ~0.
薛正良   +5 more
doaj  

Effect of Hydrodynamic Conditions on the Corrosion Mechanism of HSLA X100 Steel by EIS and EN Analysis

open access: yesSurfaces
In this research work, the influence of the electrolyte hydrodynamic conditions on the corrosion mechanism of the high-strength low-alloy (HSLA) X100 steel used in the petroleum transportation pipelines was analyzed. A Rotary Cylinder Electrode (RCE) was
Ricardo Galván-Martínez   +7 more
doaj   +1 more source

An intriguing autopsy case of gangrene intestine [PDF]

open access: yes, 2006
Background Hashimoto’s thyroiditis is one of the most common causes of hypothyroidism. Hypothyroidism is a known cause of hyperlipidemia. There is a strong correlation between coronary and mesenteric vessel atherosclerosis.
E., E.Jayashankar   +4 more
core  

Amplified biochemical oscillations in cellular systems

open access: yes, 2006
We describe a mechanism for pronounced biochemical oscillations, relevant to microscopic systems, such as the intracellular environment. This mechanism operates for reaction schemes which, when modeled using deterministic rate equations, fail to exhibit ...
A. Goldbeter   +30 more
core   +1 more source

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang   +12 more
wiley   +1 more source

The influence of chemical composition on structure of plate X100 after physical simulations of finishing rolling process with accelerated cooling

open access: yesMetalurgija, 2015
The research presented in the current paper was carried out for the experimental steel designed for plate which meets the requirements for grade X100 according to API5L.
M. Knapinski   +3 more
doaj  

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Analgesic Effects of Repetitive Transcranial Magnetic Stimulation at Different Stimulus Parameters for Neuropathic Pain: A Randomized Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The aim of the present study was to investigate the analgesic effects of repetitive transcranial magnetic stimulation over the primary motor cortex (M1‐rTMS) using different stimulation parameters to explore the optimal stimulus condition for treating neuropathic pain.
Nobuhiko Mori   +5 more
wiley   +1 more source

Purification, characterization, and expression of rat intestinal alkaline sphingomyelinase

open access: yesJournal of Lipid Research, 2002
Intestinal alkaline sphingomyelinase (SMase) has physiological roles in the digestion of sphingomyelin (SM) and clinical implications in colonic carcinogenesis.
Yajun Cheng   +3 more
doaj   +1 more source

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

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