Results 131 to 140 of about 140,451 (265)
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective To determine the risk of placental dysfunction associated with different ultrasound‐based phenotypes of impaired fetal growth in dichorionic twin pregnancies. Design Retrospective cohort study. Setting Single tertiary centre. Population Patients with dichorionic twin pregnancies delivered at ≥ 320/7 (2011–2023) (N = 753).
Ala Essalah +5 more
wiley +1 more source
BRD9 inhibition as potential treatment option for testicular germ cell tumors
Andrology, EarlyView.Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen +5 more
wiley +1 more source
Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells
Brain Pathology, EarlyView.Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son +7 more
wiley +1 more source
Bands and statistical properties of EMS exchange rates: A Monte Carlo investigation of three target zone model [PDF]
Models ...
Beetsma, R.M.W.J.
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao +12 more
wiley +1 more source
Alterations of bone proteins in medication‐related osteonecrosis of the jaw
European Journal of Oral Sciences, Volume 133, Issue 2, April 2025.Abstract Changes in the protein expression pattern of osteoblastic lineage cells from the alveolar bone (OLAB) during medication‐related osteonecrosis of the jaw (MRONJ) have rarely been investigated. This lack of information is partly because of the limited availability of healthy samples and the lack of human alveolar bone cell lines for research ...
Andrea Schubert +6 more
wiley +1 more source
The FEBS Journal, EarlyView.FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese +5 more
wiley +1 more source
Shiyou jixie, 2014 输油管道内壁的腐蚀主要由原油中的腐蚀介质引起。针对管道内壁存在氯化物腐蚀的现状，以管道出口站为研究对象，采用极化曲线测试方法和电化学阻抗谱测试技术，对目前常用的3种管线钢X70、X80和X100进行内腐蚀行为研究。研究结果表明，在试验的Cl-质量浓度范围内，呈现出低浓度Cl-促进腐蚀，高浓度Cl-抑制腐蚀的趋势；当Cl-质量浓度为40 mg/L时，3种管线钢的腐蚀速率最大，腐蚀最严重，X70耐Cl-腐蚀性能最差；当Cl-质量浓度较低时，X100的耐腐蚀性能最强；当Cl-质量浓度较高时 ...
王金刚, 李新义, 高英
doaj
The FEBS Journal, EarlyView.Cystine (Cys2) deprivation in pancreatic cancer cells induces oxidative stress that destabilizes cytosolic iron–sulfur cluster (ISC) proteins, triggering an iron‐regulatory protein (IRP)‐mediated iron‐starvation response (ISR). This leads to increased iron uptake (via TFRC), an expanded labile iron pool, and ferroptosis.
Mingjun Tan +8 more
wiley +1 more source
A noncanonical role for Jagged1 in endothelial mechanotransduction
The FEBS Journal, EarlyView.This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez +7 more
wiley +1 more source