Results 141 to 150 of about 140,451 (265)

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

open access: yesThe FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati   +4 more
wiley   +1 more source

VEGF‐Positive Mass‐Forming Intrahepatic Cholangiocarcinoma: New Subtype Based on Radiological and Molecular Pathological Analysis

open access: yesHepatology Research, EarlyView.
Radiological and molecular pathological investigation of hypervascular intrahepatic cholangiocarcinoma, typically a hypovascular tumor, revealed high VEGF expression, an increase in tumor‐associated arterial vessels, and a strong correlation with favorable prognosis.
Junya Tsuzaki   +7 more
wiley   +1 more source

Hematopathology Practice in the Digital Era: What has Changed?

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematopathology workflows are complex, since they include numerous data points necessary for guiding further testing, diagnosis, and patient management. The workflows start with complete blood cell counts, with subsequent morphologic evaluation of peripheral blood (PB) and bone marrow (BM).
Olga Pozdnyakova
wiley   +1 more source

Digital Pathology in Hematopathology: From Vision to Deployment

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Digital pathology (DP) has evolved alongside other technical advances, transforming our daily lives and diagnostic medicine. It is likely that, as in other areas of life, science, and medicine, the overall level of digitization will continue to rise, along with an increasing number of groups implementing DP.
Ryan C. Shean, Anton V. Rets
wiley   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó   +4 more
wiley   +1 more source

Plaque‐type trichoblastoma and its siblings: A (follicular tumour) family history

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Ines Bertlich   +4 more
wiley   +1 more source

Evolution of Microstructure of High-Grade Pipeline Steel

open access: yesTeshugang, 2008
With  increasing  the  strength  and  toughness  of pipeline  steel,the  corresponding  evolution  of structure  is pearlite-ferrite(X65    grade),acicular    ferite(X80    grade),particle    bainite-ferrite(X100    grade)and    lower    bainite(X120 ...
doaj  

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