Results 191 to 200 of about 140,451 (265)

Modulation of Tau Protein Neurotoxic Hallmarks by Novel σ1R Agonists/HDAC Inhibitor Dual‐Acting Compounds

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
This study explores the development of dual‐acting compounds combining σ1R agonists and histone deacetylase inhibitors (HDACi). Key findings include compound 2d and 3a's high affinity for σ1R and favorable pharmacokinetic profile and an in vivo determined σ1R agonist profile by reversing the effect of the σ1R antagonist BD‐1063.
Antonino N. Fallica   +16 more
wiley   +1 more source

[SEIOMM-SEMERGEN-semFYC-SEMG recommendations for the management of patients with osteoporosis/fragility fracture in primary care]. [PDF]

open access: yesAten Primaria
Carbonell-Abella C   +5 more
europepmc   +1 more source

Lesser omental capillary-lymphatic-venous malformation with massive intralesional hemorrhage: A case report. [PDF]

open access: yesRadiol Case Rep
Ogata H   +5 more
europepmc   +1 more source

Immune-Mediated SARS-CoV-2-Induced Orchitis Leading to Complete Testicular Failure: A Report of a Rare Case. [PDF]

open access: yesCureus
Stratis M   +7 more
europepmc   +1 more source

Common cell lysis procedures distort ribosome profiling analyses of gene expression. [PDF]

open access: yesGenome Biol
O'Connell A   +6 more
europepmc   +1 more source

Prognostic evaluation of dirty necrosis and tumor necrosis in gastric cancers. [PDF]

open access: yesSci Rep
Şeker NS   +7 more
europepmc   +1 more source

Primary meso-sigmoidal hydatid cyst: a rare presentation of echinococcosis: a case report. [PDF]

open access: yesBMC Infect Dis
Essid N   +5 more
europepmc   +1 more source

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