Results 51 to 60 of about 2,006 (215)

Leukemic Cells Hijack Stromal Bioelectricity to Reprogram the Bone Marrow Niche via CaV1.2‐Dependent Mechanisms

Advanced Science, Volume 12, Issue 39, October 20, 2025.
Leukemic blasts induce membrane depolarization in mesenchymal stromal cells (MSCs), contributing to a dysfunctional niche that favors leukemia progression. Here, it is demonstrated that restoring the expression of CaV1.2 calcium channel in AML‐MSCs repolarizes their membrane potential, reprogramming them toward a healthy phenotype.
Ambra Da Ros, Maddalena Benetton, Giulia Borella, Giorgia Longo, Giulia Borile, Alice Cani, Diego Lopez‐Pigozzi, Mario Bortolozzi, Silvia Bresolin, Claudia Tregnago, Franco Locatelli, Martina Pigazzi   +11 more
wiley   +1 more source

Preliminary Investigation of the Corrosion Behavior of Proprietary Micro-alloyed Steels in Aerated and Deaerated Brine Solutions [PDF]

, 2017
The corrosion performance of fairly new generation of micro-alloyed steels was compared in different concentrations of aerated and deaerated brines. Electrochemical polarization, weight loss and surface analyses techniques were employed.
A Dugstad, A Ismail, AH Seikh, C Palacios, D Lopez, D Matlock, D Toma, DA Lopez, DV Edmonds, E David, E Härkönen, E-SM Sherif, E-SM Sherif, F Varela, FF Eliyan, G Walter, Girish Kale, GV Chilingar, H Desouky El, H Fang, H Jung, H Moller, H Tawancy, J Guo, J Han, J Perry, JR Davis, JR Scully, L Cáceres, L Jianguo, Lawrence Onyeji, LT Popoola, M Henriquez, M Ilman, M Kermani, M Zheludkevich, MA Islam, N Ochoa, P Sarkar, Q Wu, R Vera, RC Weast, S Al-Hassan, S Nesic, S Nešić, S Wu, W Oelssner, WS Tait, X Jiang, Y Liu, Y Ren, Y Zhao, Y-S Choi, Y-S Choi, Z Yin   +54 more
core   +1 more source

Protective mechanisms against Alzheimer's disease in APOE3‐Christchurch homozygous astrocytes

Alzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract INTRODUCTION Alzheimer's disease (AD) is characterized by tau pathology, leading to neurodegeneration. Astrocytes regulate central nervous system homeostasis and influence AD progression. The APOE3‐Christchurch (APOE3‐Ch) variant is linked to AD resilience, but its protective mechanisms remain unclear.
Xinran Tian, Erica Keane Rivera, Inyoung Hwang, Arina A. Nikitina, Jennifer A. Smith, Youngsuh J. Cho, Julia Sala‐Jarque, Austin DuBose, Clare Andriola, Toby Gollan‐Myers, Kenneth S. Kosik   +10 more
wiley   +1 more source

HIPERC: a novel, high performance, economic steel concept for linepipe and general structural use [PDF]

, 2010
The HIPERC project has examined the effects of alloying elements and processing conditions in low carbon, < 0.09 wt %., niobium containing, 0.05 - 0.12 wt.%, steels.
Bremer, Sandrine, Brozda, Jerzy, De Waele, Wim, Drewett, Lyn, Gubeljak, Nenad, Liebeherr, Martin, Martin-Meizoso, A, Morbacher, Hardy, Porter, David, Zeislmair, Barbara   +9 more
core   +2 more sources

A Statistical Review of Hydrogen Effects on the Fatigue and Fracture Behavior of Steel

Fatigue &Fracture of Engineering Materials &Structures, Volume 48, Issue 9, Page 3613-3644, September 2025.
ABSTRACT This study conducts a statistical re‐analysis of experimental data from the literature to assess the influence of hydrogen on key mechanical properties, including the medium‐/high‐cycle fatigue strength and the threshold value of the stress intensity factor range.
H. Wang, N. O. Larrosa, D. Engelberg, R. Best, L. Susmel   +4 more
wiley   +1 more source

Effect of Controlled Rolling and Cooling Process on Structure and Properties of X100 Pipeline Steel

Teshugang, 2007
The controlled rolling and cooling test for a V-Nb-Ti microalloying X100 pipeline steel(0.057C,1.84Mn, 0.25Mo) has been caried out by φ350 mm 4 roll mill in laboratory.Results showed that with initial rolling temperature 1100 ℃,finishing temperature 800 ...
刘守显, 罗海文, 雍岐龙, 王瑞珍, 龙晋明   +4 more
doaj  

CO2 pipelines material and safety considerations [PDF]

, 2009
This paper presents an overview of some of the most important factors and areas of uncertainty affecting integrity and accurate hazard assessment of CO2 pipelines employed as part of the Carbon Capture and Sequestration (CCS) chain.
Bilio, M, Brown, S, Fairweather, M, IChemE, Mahgerefteh, H   +4 more
core  

Characterization of X80 and X100 Microalloyed Pipeline Steel Using Quantitative X-ray Diffraction

Metallurgical and Materials Transactions B, 2018
Quantitative X-ray diffraction characterization of four (4) X80 and three (3) X100 microalloyed steels was undertaken. The effect of through thickness position, processing parameters and composition on the measured crystallite size, microstrain and J index (relative magnitude of crystallographic texture) was determined.
Wiskel, J.B., Li, X., Ivey, D.G., Henein, H.   +3 more
openaire   +2 more sources

Comparative Analysis of Lysophosphatidic Acid Levels in Fibromyalgia and Other Painful Conditions in Female Patients

European Journal of Pain, Volume 29, Issue 6, July 2025.
ABSTRACT Background Previous work found a decrease in lysophosphatidylcholines (LPCs) in fibromyalgia (FM) serum, prompting the hypothesis that this decrease could be due to increased conversion of LPC to lysophosphatidic acid (LPA) through autotaxin (ATX). LPA has pronociceptive functions, and increased LPA levels could modulate FM pain.
Joana Menezes, Jenny E. Jakobsson, Alex Bersellini Farinotti, Emerson Krock, Matthew A. Hunt, Nils Simon, Sigita Venckute Larsson, Lars Tanum, Kim Kultima, Eva Kosek, Camilla I. Svensson   +10 more
wiley   +1 more source

Design of a (mini) wide plate specimen for strain-based weld integrity assessment [PDF]

, 2011
Wide plate tension tests are commonly executed to investigate the integrity of defective welds under a uniaxial load. The specimen can be flat or curved, depending on the geometry from which it has been extracted (plate or pipe).
De Waele, Wim, Denys, Rudi, Hertelé, Stijn, Verstraete, Matthias   +3 more
core