Results 101 to 110 of about 535,016 (293)

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun   +11 more
wiley   +1 more source

Two‐Photon 3D Printing of Functional Microstructures Inside Living Cells

open access: yesAdvanced Materials, EarlyView.
This study demonstrates 3D printing inside living cells by using two‐photon photo‐lithography. A bio‐compatible photoresist is injected into cells and selectively polymerized with a femtosecond laser, creating custom‐shaped intracellular structures with submicron resolution.
Maruša Mur   +4 more
wiley   +1 more source

Energy Consumption Optimization in Trajectory Planning for Fuel Cell Hybrid Uavs Based On HMPC

open access: yesAdvanced Robotics Research, EarlyView.
The endurance limitation of multirotor drones is a critical challenge. This study adopts a hybrid power system of fuel cells and lithium‐ion batteries. Using Nondominated Sorting Genetic Algorithm II, it integrates trajectory planning with energy management optimization.
Xindi Wang   +7 more
wiley   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

open access: yesAdvanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang   +8 more
wiley   +1 more source

Dynamic Relocalization of Histone Macroh2a1 from Centrosomes to Inactive X Chromosomes during X Inactivation [PDF]

open access: bronze, 2000
Theodore P. Rasmussen   +4 more
openalex   +1 more source

RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes

open access: gold, 2022
Hui Ma   +19 more
openalex   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

open access: yesAdvanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo   +6 more
wiley   +1 more source

The toll like receptor 7 pathway and the sex bias of systemic lupus erythematosus

open access: yesFrontiers in Immunology
Systemic lupus erythematosus (SLE) predominately affects women with a ratio of females-to-males of about 9:1. The complement of sex chromosomes may play and important role in the mechanism of the sex bias.
R. Hal Scofield   +6 more
doaj   +1 more source

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