Results 171 to 180 of about 6,305,601 (337)

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

Advanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang, Shanfeng Gao, Xiaofan Xiong, Xin Liu, Rufeng Li, Xia Wang, Lin Han, Xuan Xiao, Xiaofei Wang, Wen Li, Yongxia Chang, Yuefeng Du, Juan Yang   +12 more
wiley   +1 more source

An Inference as to the Constitution of X-chromosome in Drosophila

, 1935
Hideo Kikkawa
openalex   +2 more sources

Viability of heterozygotes for induced mutations in Drosophila melanogaster I. Irradiated X-chromosome [PDF]

, 1965
Raphael Falk, Ana Rahat, Nehama Ben-Zeev
openalex   +1 more source

The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome

Science, 2013
J. Engreitz, Amy Pandya-Jones, P. McDonel, Alexander A. Shishkin, Klára Sirokmán, Christine Surka, Sabah Kadri, Jeff Xing, A. Goren, E. Lander, K. Plath, M. Guttman   +11 more
semanticscholar   +1 more source

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

Advanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng, Zheyan Fang, Shuang Zhao, You‐en Zhang, Na Wu, Zhenyang Guo, Xin Zhong, Bixuan Jiang, Hongfei Xu, Hangnan Hong, Zhentao Zhang, Mukaddas Abdurahman, Xueting Yu, Jilong Geng, Xiansu Nie, Supuya Abuduwahapi, Dong Huang, Gang Zhao, Wenbin Zhang, Hao Lu, Li Shen, Xin Zhao, Zhaoyang Chen, Junjie Guo, Hongchao Zheng, Yue He, Sanwu Wu, Jiayin Peng, Jiawen Song, Xiao Wang, Haomin Li, Yuli Huang, Shengying Qin, Haojie Lu, Xiangdong Wang, Jianguo Zhao, Lei Huang, Yun Zhao, Peng Li, Junbo Ge, Hua Li   +40 more
wiley   +1 more source

Controlling elements in the mouseX-chromosome: I. Interaction with the X-linked genes [PDF]

, 1969
B.M. Cattanach, C.E. Pollard, J. N. Perez   +2 more
openalex   +1 more source

Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond

Advanced Science, EarlyView.
Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao, Yunfan Lin, Pei Lin, Ye Lu, Jiarong Zheng, Xu Chen, Zihao Zhou, Li Cui   +7 more
wiley   +1 more source

SCRIPT: Predicting Single‐Cell Long‐Range Cis‐Regulation Based on Pretrained Graph Attention Networks

Advanced Science, EarlyView.
SCRIPT is a novel method inferring single‐cell cis‐regulatory relationships (CRRs) from transcriptomic and chromatin accessibility data. SCRIPT incorporates two key innovations: graph causal attention networks supported by empirical CRR evidence, and representation learning enhanced through pretraining on atlas‐scale single‐cell data.
Yu Zhang, Baole Wen, Yifeng Jiao, Yuchen Liu, Xin Guo, Yushuai Wu, Jiyang Li, Limei Han, Yinghui Xu, Xin Gao, Yuan Qi, Yuan Cheng, Ying He, Weidong Tian   +13 more
wiley   +1 more source

Assessment of X Chromosome Centromere Instability in Alzheimer's Disease: A Quantitative FISH Approach. [PDF]

Curr Issues Mol Biol
Spremo-Potparević B, Popović P, Topalović D, Pirković A, Perry G, Živković L.   +5 more
europepmc   +1 more source

The Implication of Early Chromatin Changes in X Chromosome Inactivation

Cell, 2019
J. J. Żylicz, Aurélie Bousard, Kristina Žumer, François Dossin, Eusra Mohammad, S. T. da Rocha, B. Schwalb, L. Syx, F. Dingli, D. Loew, P. Cramer, E. Heard   +11 more
semanticscholar   +1 more source