Results 191 to 200 of about 6,270,911 (362)

The Implication of Early Chromatin Changes in X Chromosome Inactivation

open access: yesCell, 2019
J. J. Żylicz   +11 more
semanticscholar   +1 more source

IR783‐Stabilized Nanodrugs Enhance Anticancer Immune Response by Synergizing Oxidation Therapy and Epigenetic Modulation

open access: yesAdvanced Science, EarlyView.
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu   +6 more
wiley   +1 more source

Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing

open access: yesScience, 2016
Chun-Kan Chen   +9 more
semanticscholar   +1 more source

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen   +12 more
wiley   +1 more source

Prevalence of CNVs on the X chromosome in patients with neurodevelopmental disorders. [PDF]

open access: yesMol Cytogenet
Tolmacheva EN   +16 more
europepmc   +1 more source

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