Results 241 to 250 of about 6,270,911 (362)

LncRNA‐MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid–Liquid Phase Separation

open access: yesAdvanced Science, EarlyView.
This study has identified lncRNA‐MEG3 as a key regulator of muscle mass, promoting slow‐twitch muscle fibers and preventing muscle atrophy. By stabilizing the SUZ12/PRC2 complex through liquid–liquid phase separation (LLPS), lncRNA‐MEG3 influences mitochondrial function and lipid metabolism.
Yilong Yao   +15 more
wiley   +1 more source

B cell stimulation changes the structure and higher-order organization of the inactive X chromosome. [PDF]

open access: yesCell Rep
Sierra I   +13 more
europepmc   +1 more source

H 3 -THYMIDINE UPTAKE BY A RING X CHROMOSOME IN A HUMAN FEMALE

open access: green, 1964
Janet D. Rowley   +3 more
openalex   +2 more sources

PABPN1 Couples the Polyadenylation and Translation of Maternal Transcripts to Mouse Oocyte Meiotic Maturation

open access: yesAdvanced Science, EarlyView.
This study reveals that cytoplasmic PABPN1 is essential for mouse oocyte meiotic maturation by coordinating polyadenylation, translation, and degradation of maternal mRNAs. Pabpn1 knockout disrupts CDK1 activation, spindle formation, and chromosome alignment by impairing maturation‐promoting factor (MPF) regulation and BTG4‐mediated deadenylation ...
Xing‐Xing Dai   +9 more
wiley   +1 more source

X-chromosome inactivation and escape

open access: yesJournal Genetika, 2015
C. Disteche, J. B. Berletch
semanticscholar   +1 more source

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