Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
The Emerging Role of Explainable Artificial Intelligence in EEG-Based Autism Research: A Systematic Review. [PDF]
Martelli ME +6 more
europepmc +1 more source
On Using the Shapley Value for Anomaly Localization: A Statistical Investigation
ABSTRACT Recent publications have suggested using the Shapley value for anomaly localization for sensor data systems. We use a reasonable statistical model for the classifiers required to compute the Shapley value to provide repeatable and rigorous analysis in the anomaly localization application.
Rick S. Blum +2 more
wiley +1 more source
Explainable AI in healthcare: a systematic review of XAI use cases in imaging, diagnostics, and rehabilitation. [PDF]
Aravindkumar A +4 more
europepmc +1 more source
In this work, we have performed human‐based evaluation of three post hoc explainability techniques, Local Interpretable Model Agnostic Explanations (LIME), Shapely Additive Explanations (SHAP), and integrated Gradients (IG) for a multilingual Bidirectional Encoder Representations from Transformers (mBERT) based binary and multi‐label misogyny ...
Sargam Yadav +2 more
wiley +1 more source
Cross‐Method Explanation Stability Under Prediction‐Preserving Perturbations in Explainable AI
The cross‐method analysis showed common vulnerability patterns across gradient‐based and perturbation‐based explainers, whereas Grad‐CAM demonstrated a specific ability to be resilient. Further discussion revealed that, before prediction changes with increasing ε, explanation divergence could already have commenced, indicating that further explanation ...
Muhammad Hasnain +4 more
wiley +1 more source
Symmetry-guided explainable deep learning for colon cancer diagnosis: model benchmarking, cross-validation, statistical analysis, and explainability via ablation studies. [PDF]
Solanki A +5 more
europepmc +1 more source
Stacked Ensemble Model With Explainable AI for Early Detection of Heart Disease
ABSTRACT Heart disease (HD) is still one of the most common causes of death around the world. Early detection is very important, but it is often hard to do because the symptoms are not specific and the models are not very clear. We propose a two‐layer stacked ensemble that combines four base learners—Support Vector Machine, K‐Nearest Neighbors, Naïve ...
Nazmun Nahar +8 more
wiley +1 more source
Emotion-Adaptive Large Language Model-Driven Clinical Decision Support: User Evaluation of the Empathic Clinical Decision Support System Framework for Trust and Explainability. [PDF]
Zhang T, Bae SW, Chung T, Dey AK.
europepmc +1 more source
ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal +2 more
wiley +1 more source

