Results 91 to 100 of about 6,787 (215)

Anti-Tumor Xanthones from Garcinia nujiangensis Suppress Proliferation, and Induce Apoptosis via PARP, PI3K/AKT/mTOR, and MAPK/ERK Signaling Pathways in Human Ovarian Cancers Cells

open access: yesDrug Design, Development and Therapy, 2020
Zhongyan Tang,1,* Lihua Lu,2,* Zhengxiang Xia3 1Department of Emergency and Critical Care Medicine, Jin Shan Hospital, Fudan University, Shanghai 201508, People’s Republic of China; 2Department of Neonatology, International Peace Maternity and ...
Tang Z, Lu L, Xia Z
doaj  

Effect of Xanthone and 1-Hydroxy Xanthone on the Dipole Potential of Lipid Membranes

open access: yesColloid and Interface Science Communications, 2018
Abstract Xanthone (Xa) and 1-OH Xanthone (1-OHXa) in 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) membranes increase the dipole potential. Results with 1,2-di-O-tetradecyl-sn-glycero-3-phosphocholine (Ether PC), lacking carbonyl groups, indicate that the CO dipole of Xa molecule does not contribute to the increase of dipole potential. Molecular
Cejas, Jimena del Pilar   +7 more
openaire   +2 more sources

Synthesis of caged Garcinia xanthone analogues [PDF]

open access: yes, 2009
A new synthetic strategy is developed toward the synthesis of the caged Garcinia xanthone analogues. The key to the strategy is a Pd-catalyzed reverse prenylation reaction.
Cho, Woo Cheal
core  

Preparation and characterization of mangiferin-loaded lipid nanocapsules

open access: yesArchives of Pharmaceutical Sciences Ain Shams University, 2023
Mangiferin (Mgf), a xanthone glucoside of natural origin, is well known to possess different pharmacological actions such as analgesic, antiviral, antidiabetic, anti-inflammatory, hepatoprotective, and antitumor. However, concerning water solubility it
Sara S. Barakat   +3 more
doaj  

Transcription profiling of the Neurospora crassa response to a group of synthetic (thio)xanthones and a natural acetophenone

open access: yesGenomics Data, 2015
Xanthones are a class of heterocyclic compounds characterized by a dibenzo-γ-pyrone nucleus. Analysis of their mode of action in cells, namely uncovering alterations in gene expression, is important because these compounds have potential therapeutic ...
A. Pedro Gonçalves   +9 more
doaj   +1 more source

Coumarins, Xanthones and Related Compounds

open access: yesMolecules, 2016
It has long been known that coumarins (γ-pyrones) and xanthones (α-pyrones) together form a large class of naturally occurring compounds exhibiting a wide range of biological activities.[...]
openaire   +3 more sources

QSAR and docking studies on xanthone derivatives for anticancer activity targeting DNA topoisomerase IIα

open access: yes, 2014
Sarfaraz Alam, Feroz KhanMetabolic and Structural Biology Department, Central Institute of Medicinal and Aromatic Plants, Council of Scientific and Industrial Research, Lucknow, Uttar Pradesh, IndiaAbstract: Due to the high mortality rate in India, the ...
Alam S, Khan F
core  

Chemical syntheses of polycyclic xanthone analogues

open access: yes, 2023
Polycyclic xanthones are a family of structurally complex natural products with diverse and potent biological activity and thus attract much attention in organic and medicinal communties.
Liang, Han Bin
core  

Synthesis of xanthone derivatives by microwave-assisted methods [PDF]

open access: yes, 2008
Synthesis of Xanthone Derivatives by Microwave-assisted Methods Petr Vrbata This diploma thesis deals with preparation of xanthone derivatives as inhibitors of growth of human cancer cell lines. A new methodology for synthesis of dihydropyranoxanthones 1
Vrbata, Petr
core  

Xanthones and Cancer

open access: yes, 2020
Xanthones are a class of heterocyclic natural products that have been widely studied for their pharmacological potential. In fact, they have been serving as scaffolds for the design of derivatives focusing on drug development. One of the main study targets of xanthones is their anticancer activity. Several compounds belonging to this class have already
Klein-Júnior, Luiz C   +5 more
openaire   +1 more source

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