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Xanthones as Potential Antioxidants
Current Medicinal Chemistry, 2013Xanthones (dibenzo-γ-pyrones) constitutes an important class of oxygenated heterocycles and occur as secondary metabolites in plants and microorganisms. They are known for various biological activities such as antioxidant, monoamine oxidase inhibitor, antihypertensive, hepatoprotective, antithrombotic, antifungal and anticancer.
S S, Panda +3 more
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Synthesis of Xanthones: An Overview
Current Medicinal Chemistry, 2005Among the known synthetic routes to obtain xanthones, the Grover, Shah, and Shah reaction, the cyclodehydration of 2, 2-dihydroxybenzophenones and electrophilic cycloacylation of 2-aryloxybenzoic acids are the most popular methods. Due to important biological applications of xanthones, some synthetic strategies leading to more complex derivatives ...
M E, Sousa, M M M, Pinto
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Xanthones-A Structural Perspective
Current Medicinal Chemistry, 2005Xanthones, synthesized or isolated from a natural source, display a wide range of biological and pharmacological activities. In a few cases, their chemical characterization has involved the structure elucidation by single crystal X-ray diffraction.
L, Gales, A M, Damas
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Xanthones of Comastoma pedunlulatum
China Journal of Chinese Materia Medica, 2010The xanthones in the ethyl acetate extract of Comastoma pedunlulatum were investigated. The chromatographic and spectroscopic techniques were used to isolate and identify the constituents. Nine xanthones were isolated from the active parts of the ethyl acetate portion of the 70% ethanolic extract of C.
Yi, Yuan +3 more
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Xanthone Analogue of Geiparvarin
Archiv der Pharmazie, 1985AbstractThe synthesis and the pharmacological properties of the xanthone analogue of geiparvarin, a naturally occurring antitumor coumarin, are described.
P, Valenti +5 more
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Xanthone: A Promising Antimycobacterial Scaffold
Medicinal Chemistry, 2021Background: Tuberculosis (TB) is one of the infectious diseases associated with high rate of morbidity and mortality and still remains one of the top-ten leading causes of human death in the world. The development of new anti-TB drugs is mandatory due to the existence of latent infection as well as the expansion of the resistant Mycobacterium ...
Tilal, Elsaman +4 more
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Allylamine Type Xanthone Antimycotics
Archiv der Pharmazie, 1998A number of xanthone derivatives bearing the basic chain of naftifine and butenafine antimycotics in 1, 2, 3, and 4 nuclear positions are described. The in vitro antifungal activity against representative strains of molds and yeasts is reported. Only butenafine xanthone analogues show significant activity against Cryptococcus neoformans, in particular ...
I. SALMOIRAGHI +3 more
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Secoiridoids and Xanthones in the Genus Centaurium
Planta Medica, 1981Overground parts of Centaurium spicatum (L.) Fritsch (Gentianaceae) from two different habitats have been investigated on their content of Secoiridoid glucosides. Sweroside (I), Swertiamarin (II) and gentiopicrin (III) (= gentiopicroside) have been identified. In plant material of C. spicatum from both habitats sweroside is the major compound. In plant
W G, van der Sluis, R P, Labadie
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A New Regiospecific Preparation of Xanthones
Organic Letters, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Frank M, Hauser, Warren A, Dorsch
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Acta Crystallographica Section C Crystal Structure Communications, 1990
C 13 H 8 O 2 cristallise dans P2 1 2 1 2 1 avec a=14,072, b=13,627, c=4,878A, Z=4 ; affinement jusqu'a R=0,077. La molecule est plane sauf pour l'atome O du carbonyl (0,13A hors du plan). Les cycles benzene ne sont pas des hexagones reguliers mais la distorsion est symetrique et la molecule a la symetrie C 2v approximative. Il n'y a pas de distances
S. Onuma, K. Iijima, I. Oonishi
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C 13 H 8 O 2 cristallise dans P2 1 2 1 2 1 avec a=14,072, b=13,627, c=4,878A, Z=4 ; affinement jusqu'a R=0,077. La molecule est plane sauf pour l'atome O du carbonyl (0,13A hors du plan). Les cycles benzene ne sont pas des hexagones reguliers mais la distorsion est symetrique et la molecule a la symetrie C 2v approximative. Il n'y a pas de distances
S. Onuma, K. Iijima, I. Oonishi
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