Results 31 to 40 of about 11,180 (215)

Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones as Potential p53-Activating Agents

open access: yesMolecules, 2019
Xanthone scaffold has been regarded as an attractive chemical tool in the search for bioactive molecules with antitumor activity, and in particular two xanthone derivatives, 12-hydroxy-2,2-dimethyl-3,4-dihydro-2H,6H-pyrano [3,2-b]xanthen-6-one (4) and 3 ...
Agostinho Lemos   +7 more
doaj   +1 more source

Tetraoxygenated naturally occurring xanthones

open access: yesPhytochemistry, 2000
This review, with 350 references, gives information on the chemical study of 234 naturally occurring tetraoxygenated xanthones in 12 families, 53 genus and 182 species of higher plants, and two which are described as fungal and lichen metabolites. The value of these groups of substances in connection with pharmacological activity and therapeutic use of
V, Peres, T J, Nagem, F F, de Oliveira
openaire   +3 more sources

Characterization of Antioxidant and α-Glucosidase Inhibitory Compounds of Cratoxylum formosum ssp. pruniflorum and Optimization of Extraction Condition

open access: yesAntioxidants, 2023
Cratoxylum formosum ssp. pruniflorum (Kurz.) Gogel (Guttiferae), called kuding tea, is widely distributed in Southeast Asia. In this study, the constituents and biological activity of C. formosum ssp. pruniflorum were investigated. Extract of its leaves,
Heewon An   +10 more
doaj   +1 more source

Cytoprotective and Anti-genotoxic Effects of Xanthone Derivatives from Garcinia mangostana Against H2O2 Induced PBMC Cell and Blood Leukocytes Damage of Normal and Type 2 Diabetes Volunteers

open access: yesWalailak Journal of Science and Technology, 2018
Hyperglycemia is well-known for inducing cellular oxidative damage in type II diabetes (T2D) patients. This research addressed the cytoprotective and anti-genotoxic effect of xanthone derivatives from Garcinia mangostana against hydrogen peroxide (H2O2 ...
Naymul KARIM   +2 more
doaj   +1 more source

Design and Experimental Validation of a Photocatalyst Recommender Based on a Large Language Model

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Choosing a photocatalyst for a given reaction can be challenging due to complex mechanisms and multiple parameters that govern the outcome of a photocatalyzed reaction. Herein, we disclose a machine learning (ML) model that can suggest catalysts for a given reaction using an online portal.
Francis Millward   +13 more
wiley   +2 more sources

Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana

open access: yesMolecules, 2014
Bioassay-guided fractionation of an ethanol extract of the pericarps of Garcinia mangostana led to the isolation of two new prenylated xanthones, named 1,3,7-trihydroxy-2-(3-methyl-2-butenyl)-8-(3-hydroxy-3-methylbutyl)-xanthone (1) and 1,3,8 ...
Zeng Xu   +7 more
doaj   +1 more source

Chemometrically Assisted Optimization of Pregabalin Fluorescent Derivatization Reaction with a Novel Xanthone Analogue and Validation of the Method for the Determination of Pregabalin in Bulk via a Plate Reader

open access: yesMolecules, 2022
Quantitation of chromophore-free analytes is always a challenge. To this purpose, derivatization of the analyte constitutes a common strategy, leading to a product with a strong signal. In the current study, a novel xanthone analogue was utilized for the
Nikolaos Kritikos   +6 more
doaj   +1 more source

Structures, Activities and Drug-Likeness of Anti-Infective Xanthone Derivatives Isolated from the Marine Environment: A Review

open access: yesMolecules, 2019
Marine organisms represent almost half of total biodiversity and are a very important source of new bioactive substances. Within the varied biological activities found in marine products, their antimicrobial activity is one of the most relevant ...
Daniela R. P. Loureiro   +6 more
semanticscholar   +1 more source

Antiprotozoal and Antibacterial Activity of Ravenelin, a Xanthone Isolated from the Endophytic Fungus Exserohilum rostratum

open access: yesMolecules, 2021
The natural compound ravenelin was isolated from the biomass extracts of Exserohilum rostratum fungus, and its antimicrobial, antiplasmodial, and trypanocidal activities were evaluated.
Jeferson Rodrigo Souza Pina   +12 more
doaj   +1 more source

Xanthone impairs platelet activation and thrombus formation

open access: yesPlatelets
Xanthone, a naturally occurring oxygenated heterocyclic compound from the Garcinia family with known anti-cancer, antimicrobial, antioxidant, anti-inflammatory, and antiviral properties, has an unclear role in platelet function.
Hui Zhu   +8 more
doaj   +1 more source

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