Results 31 to 40 of about 7,063 (213)

LC-QTOF-MS analysis of xanthone content in different parts of Garcinia mangostana and its influence on cholinesterase inhibition

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Mangosteen is one of the best tasting tropical fruit widely cultivated in Southeast Asia. This study aimed to quantify xanthone content in different parts of Garcinia mangostana by LC-QTOF-MS and determine its influence on their cholinesterase inhibitory
Kooi Yeong Khaw, Chun Wie Chong, Vikneswaran Murugaiyah   +2 more
doaj   +1 more source

Antiprotozoal and Antibacterial Activity of Ravenelin, a Xanthone Isolated from the Endophytic Fungus Exserohilum rostratum

Molecules, 2021
The natural compound ravenelin was isolated from the biomass extracts of Exserohilum rostratum fungus, and its antimicrobial, antiplasmodial, and trypanocidal activities were evaluated.
Jeferson Rodrigo Souza Pina, João Victor Silva-Silva, Josiwander Miranda Carvalho, Heriberto Rodrigues Bitencourt, Luciano Almeida Watanabe, Juan Matheus Pereira Fernandes, Guilherme Eduardo de Souza, Anna Caroline Campos Aguiar, Rafael Victorio Carvalho Guido, Fernando Almeida-Souza, Kátia da Silva Calabrese, Patrícia Santana Barbosa Marinho, Andrey Moacir do Rosario Marinho   +12 more
doaj   +1 more source

A free radical process for oxidation of hydrocarbons promoted by nonmetal xanthone and tetramethylammonium chloride under mild conditions

, 2009
A nonmetal catalytic system consisting of N-hydroxyphthalimide, xanthone, and tetramethylammonium chloride was developed. A wide range of hydrocarbons could be oxidized efficiently with dioxygen under mild conditions.
Sun, Zhiqiang, Xu, Jie, Zhang, Wei, Miao, Hong, Du, Zhongtian, Ma, Hong, 徐杰   +6 more
core   +1 more source

Cytoprotective and Anti-genotoxic Effects of Xanthone Derivatives from Garcinia mangostana Against H2O2 Induced PBMC Cell and Blood Leukocytes Damage of Normal and Type 2 Diabetes Volunteers

Walailak Journal of Science and Technology, 2018
Hyperglycemia is well-known for inducing cellular oxidative damage in type II diabetes (T2D) patients. This research addressed the cytoprotective and anti-genotoxic effect of xanthone derivatives from Garcinia mangostana against hydrogen peroxide (H2O2 ...
Naymul KARIM, Lanchakon CHANUDOM, Jitbanjong TANGPONG   +2 more
doaj   +1 more source

Effect of 1-Carbaldehyde-3,4-dimethoxyxanthone on Prostate and HPV-18 Positive Cervical Cancer Cell Lines and on Human THP-1 Macrophages

Molecules, 2021
Xanthone derivatives have shown promising antitumor properties, and 1-carbaldehyde-3,4-dimethoxyxanthone (1) has recently emerged as a potent tumor cell growth inhibitor.
Rui Medeiros, Bruno Horta, Joana Freitas-Silva, Jani Silva, Francisca Dias, Emília Sousa, Madalena Pinto, Fátima Cerqueira   +7 more
doaj   +1 more source

Cytotoxic Prenylated Xanthones from the Pericarps of Garcinia mangostana

Molecules, 2014
Bioassay-guided fractionation of an ethanol extract of the pericarps of Garcinia mangostana led to the isolation of two new prenylated xanthones, named 1,3,7-trihydroxy-2-(3-methyl-2-butenyl)-8-(3-hydroxy-3-methylbutyl)-xanthone (1) and 1,3,8 ...
Zeng Xu, Lei Huang, Xiao-Hong Chen, Xiao-Feng Zhu, Xiao-Jun Qian, Gong-Kan Feng, Wen-Jian Lan, Hou-Jin Li   +7 more
doaj   +1 more source

Dynamics of unfolded and [alpha]-helical polypeptide chains [PDF]

, 2007
The aim of this thesis was the investigation of the dynamics of elementary steps in protein folding. During folding, the polypeptide chain explores the free energy surface and first interactions are established. These interactions lead to formation of
Fierz, Beat
core   +1 more source

From Natural Products to New Synthetic Small Molecules: A Journey through the World of Xanthones

Molecules, 2021
This work reviews the contributions of the corresponding author (M.M.M.P.) and her research group to Medicinal Chemistry concerning the isolation from plant and marine sources of xanthone derivatives as well as their synthesis, biological/pharmacological
Madalena M. M. Pinto, Andreia Palmeira, Carla Fernandes, Diana I. S. P. Resende, Emília Sousa, Honorina Cidade, Maria Elizabeth Tiritan, Marta Correia-da-Silva, Sara Cravo   +8 more
doaj   +1 more source

Recent cancer drug development with xanthone structures

, 2009
Objectives Xanthones are simple three-membered ring compounds that are mainly found as secondary metabolites in higher plants and microorganisms. Xanthones have very diverse biological profiles, including antihypertensive, antioxidative,
Younghwa Na
core   +1 more source

Xanthone impairs platelet activation and thrombus formation

Platelets
Xanthone, a naturally occurring oxygenated heterocyclic compound from the Garcinia family with known anti-cancer, antimicrobial, antioxidant, anti-inflammatory, and antiviral properties, has an unclear role in platelet function.
Hui Zhu, Ruoyi Shen, Chenyue Wang, Xiaoyue Zu, Yanlong Zhou, Long Yang, Yueyue Sun, Ping Fu, Jun Lu   +8 more
doaj   +1 more source