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Disrupting Androgen Receptor Functionality with Xanthones from the Mangosteen (Garcinia mangostana) Fruit [PDF]

open access: goldProceedings, 2020
The Southeast Asian mangosteen (Garcinia mangostana) contains a class of phytochemicals known as xanthones that possess extensive biological activity. Applications of xanthones, including the most prominent, alpha-mangostin, have been shown to possess ...
Jeremy J. Johnson
doaj   +2 more sources

In Vitro and In Vivo Antiangiogenic Activity of Caged Polyprenylated Xanthones Isolated from Garcinia hanburyi Hook. f. [PDF]

open access: goldMolecules, 2013
Eleven known caged polyprenylated xanthones 1–11 were isolated from the resin of Garcinia hanburyi Hook. f., and their structures were identified by their MS, NMR and UV spectra.
Jianhong Yang   +5 more
doaj   +2 more sources

Potential Of Mangosteen Xanthones As Anti-Oral Cancer Agents By Induction Of Apoptosis [PDF]

open access: yesInsisiva Dental Journal, 2012
The pericarp of mangosteen (Garcinia mangostana L.) is rich in various xanthones that are known to possess unique biological activities. The aim of this study was to determine of antiproliferative and cytotoxic activities of mangosteen xanthones.
Yani Corvianindya Rahayu
doaj   +2 more sources

Naturally Occurring Xanthones and Their Biological Implications [PDF]

open access: yesMolecules
Xanthones are chemical substances in higher plants, marine organisms, and lower microorganisms. The most prevalent naturally occurring sources of xanthones are those belonging to the families Caryophyllaceae, Guttiferae, and Gentianaceae.
Ayodeji O. Oriola, Pallab Kar
doaj   +2 more sources

A Review of the Influence of Various Extraction Techniques and the Biological Effects of the Xanthones from Mangosteen (Garcinia mangostana L.) Pericarps

open access: yesMolecules, 2022
Xanthones are significant bioactive compounds and secondary metabolites in mangosteen pericarps. A xanthone is a phenolic compound and versatile scaffold that consists of a tricyclic xanthene-9-one structure. A xanthone may exist in glycosides, aglycones,
Vasin Yuvanatemiya   +6 more
doaj   +1 more source

Hydrogen-Bonded Xanthones as Potential UV Absorbers: The Synthesis of Xanthones from Bio-Renewable Cardanol Utilizing a Ceric Ammonium Sulfate (CAS)-Mediated Oxidation Reaction

open access: yesSynOpen, 2022
The synthesis of hydrogen-bonded xanthones by using biorenewable hydrogenated cardanol (3-pentadecylphenol) is described. Hydrogenated cardanol was initially converted into various hydroxybenzophenones.
Fatema Jagot   +5 more
doaj   +1 more source

Review on the Cytotoxic and Antimicrobial Properties of Xanthones from Cratoxylum cochinchinense

open access: yesJournal of Tropical Life Science, 2023
Cratoxylum cochinchinense is a perennial plant found in Southeast Asia, having diverse terminologies in various Southeast Asian countries. It has been traditionally used as medicine, tea and food spice.
Su Ying Lee   +5 more
doaj   +1 more source

Marine-Derived Xanthone from 2010 to 2021: Isolation, Bioactivities and Total Synthesis

open access: yesMarine Drugs, 2022
Marine life has proved to be an invaluable source of new compounds with significant bioactivities, such as xanthones. This review summarizes the advances made in the study of marine-derived xanthones from 2010 to 2021, from isolation towards synthesis ...
Ana C. S. Veríssimo   +2 more
doaj   +1 more source

Xanthones protects lead-induced chronic kidney disease (CKD) via activating Nrf-2 and modulating NF-kB, MAPK pathway

open access: yesBiochemistry and Biophysics Reports, 2020
Xanthones from a tropical fruit of Garcinia mangostana L. is known to possess a wide spectrum of pharmacologic properties, including antioxidant, anti-bacterial, anti-inflammatory, and antidiabetic activities.
Mohammad Nasiruddin Rana   +2 more
doaj   +1 more source

Investigation of bacterial neuraminidase inhibition of xanthones bearing geranyl and prenyl groups from Cratoxylum cochinchinense

open access: yesFrontiers in Chemistry, 2023
Introduction: The root of Cratoxylum cochinchinense has been widely used as Chinese folk medicine to cure fevers, burns, and abdominal complications because it contains various bioactive metabolites such as xanthones, triterpenes, and flavonoids. In this
Jeong Yoon Kim   +6 more
doaj   +1 more source

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