Development of Polymeric Nanoparticles of Garcinia mangostana Xanthones in Eudragit RL100/RS100 for Anti-Colon Cancer Drug Delivery [PDF]
, 2015 Xanthones are a group of oxygenated heterocyclic compounds with anticancer properties, but poor aqueous solubility and low oral bioavailability hinder their therapeutic application.
Abdalrahim F. A., Aisha +4 more
core +3 more sources
Xanthones Content in Swertia multicaulis D. Don from Nepal
Molecules, 2018 The medicinal plant Swertia multicaulis D. Don was collected in Rasuwa District (Nepal) and the xanthone content of its ethyl acetate extracts was studied. The total amount of xanthones in S.
Binu Timsina +6 more
doaj +1 more source
Xanthone biosynthesis in Hypericum perforatum cells provides antioxidant and antimicrobial protection upon biotic stress [PDF]
, 2009 Xanthone production in Hypericum perforatum (HP) suspension cultures in response to elicitation by Agrobacterium tumefaciens co-cultivation has been studied. RNA blot analyses of HP cells co-cultivated with A.
Conceição, Luís F. R. +3 more
core +1 more source
Improvement of the inhibitory effect of xanthones on NO production by encapsulation in PLGA nanocapsules [PDF]
, 2005 For the first time the inhibitory effect of xanthone and 3-methoxyxanthone on nitric oxide (NO) production by IFN-gamma/LPS activated J774 macrophage cell line is reported.
Barbosa, CM +4 more
core +1 more source
Chemical and Biological Research on Herbal Medicines Rich in Xanthones
Molecules, 2017 Xanthones, as some of the most active components and widely distributed in various herb medicines, have drawn more and more attention in recent years.
Jingya Ruan +7 more
doaj +1 more source
Xanthones, A Promising Anti-Inflammatory Scaffold: Structure, Activity, and Drug Likeness Analysis
Molecules, 2020 Inflammation is the body’s self-protective response to multiple stimulus, from external harmful substances to internal danger signals released after trauma or cell dysfunction.
Zheling Feng +4 more
doaj +1 more source
Xanthone biosynthesis and accumulation in calli and suspended cells of Hypericum androsaemum [PDF]
, 2000 Calli and suspended cells of Hypericum androsaemum accumulated high levels of 1,3,5,6 and 1,3,6,7 oxygenated xanthones. The major compounds include simple oxygenated xanthones or derivatives with prenyl, pyran or methoxyl groups, four of them being new
Andrade, Paula B. +4 more
core +1 more source
Structure–Activity Relationship of Xanthones as Inhibitors of Xanthine Oxidase
Molecules, 2018 Polygala plants contain a large number of xanthones with good physiological activities. In our previous work, 18 xanthones were isolated from Polygala crotalarioides.
Ling-Yun Zhou +5 more
doaj +1 more source
2,3-Diarylxanthones as potential inhibitors of Arachidonic acid metabolic pathways [PDF]
, 2017 In response to an inflammatory stimulus, arachidonic acid (AA), the main polyunsaturated fatty acid present in the phospholipid layer of cell membranes, is released and metabolized to a series of eicosanoids.
Feliciano, Manuel +7 more
core +3 more sources
Tetraoxygenated naturally occurring xanthones
Phytochemistry, 2000 This review, with 350 references, gives information on the chemical study of 234 naturally occurring tetraoxygenated xanthones in 12 families, 53 genus and 182 species of higher plants, and two which are described as fungal and lichen metabolites. The value of these groups of substances in connection with pharmacological activity and therapeutic use of
V, Peres, T J, Nagem, F F, de Oliveira
openaire +3 more sources