Results 121 to 130 of about 77,053 (291)

Identification of xenobiotics interfering with corticosteroid - androgen balance

open access: yes, 2023
The preset in this thesis research provides valuable insights into the complex interplay between xenobiotics and corticosteroids-androgens balance. Through an extensive review of the literature, experimental investigations, and data analysis, several ...
Kędzierski, Jacek
core  

Do Microplastics in Soil Influence the Bioavailability of Sulfamethoxazole to Plants?

open access: yesPlants
The presence of pharmaceuticals and MPs in soil raises concern due to their potential impact on plant health and ecosystem stability. This study investigates the impact of MPs on the bioavailability and phytotoxicity of sulfamethoxazole (SMX) using ...
Anna Parus   +3 more
doaj   +1 more source

Xenobiotics removal from polluted water by a multifunctional constructed wetland

open access: yes, 2002
Removal efficiencies on xenobiotics from polluted water in a twin-shaped constructed wetland consisting of a vertical flow chamber with the crop plant Colocasia esculenta L. Schott and a reverse vertical flow one with Ischaemum aristatum var.
Wolfgang Grosse   +4 more
core  

Mutagenic activation of xenobiotics by plant enzymes.

open access: yes, 1988
Genetic evidence has indicated that plants can activate certain xenobiotics to mutagens, but biochemical evidence is as yet scarce. Nevertheless, plant microsomal enzymes and peroxidases have been shown to form reactive intermediates, the best studied ...
Sandermann, H.J.
core   +1 more source

Multi‐omics–driven precision medicine

open access: yesiMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li   +20 more
wiley   +1 more source

Effects of estrogenic xenobiotics on human and mouse spermatozoa

open access: yes, 2006
OBJECTIVE: To investigate human sperm responsiveness to the estrogenic xenobiotic genistein and seek further information regarding the mechanism of action of estrogenic xenobiotics using mouse spermatozoa.
Fraser, L R   +3 more
core   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger   +3 more
wiley   +1 more source

Qualitative determination of key emerging xenobiotics in mixed wastewater discharge [PDF]

open access: yes, 2016
Nowdays, it is unattainable to follow, detect or identify all the chemicals that are excreted into the environmental aquatic bodies. The number of chemicals introduced into the environment in modified structures, as metabolites or as mixtures of chemical
Mihajlović Ivana   +5 more
core  

Bisphenol Analog‐Induced Cytotoxicity: Unraveling Endoplasmic Reticulum (ER) Stress and Apoptotic Pathways

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is increasingly replaced by structural analogs, yet their safety remains insufficiently characterized. This study investigated whether BPA and selected analogs, bisphenol AF (BPAF), bisphenol AP (BPAP), bisphenol P (BPP), and bisphenol E (BPE), induce cytotoxicity through activation of endoplasmic reticulum (ER) stress and ...
Rafia Afroze Rifa, Ramon Lavado
wiley   +1 more source

Detoxification of 3,4-dichloroaniline in soybean by n-malonylation [PDF]

open access: yes, 2003
3,4-Dichloroaniline (DCA), the degradation product of certain herbicides, is not readily degraded by micro-organisms and, due to its persistence in the environment, is considered to be a reference xenobiotic.
Lao, Si-houy, Lao, S-H.
core  

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