Water and Environment Journal, EarlyView.This show the biodegradation of spent lubricating oil by Bacillus sp. and a marine bacterial consortium. The consortium showed higher growth, biosurfactant production and oil removal efficiency than the isolated strain, highlighting its potential for bioremediation ABSTRACT Spent automotive lubricating oil contains complex hydrocarbons and heavy metals,
Letícia Carvalho Eustaquio Costa +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend New approach methodologies (NAMs) to test the pharmaco‐ and chemicokinetics of compound transfer across the human placental barrier in late pregnancy. Abstract This review addresses an important and timely topic at the intersection of placental biology with respect to barrier transfer kinetics, toxicology and mathematical ...
Paul Brownbill, Eleanor Doman
wiley +1 more source
Environmental shaping of tolerance failure in autoimmune liver diseases: a phenotype-specific framework with primary biliary cholangitis as the strongest model. [PDF]
J Transl AutoimmunMirowski K +2 more
europepmc +1 more source
Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells
The Journal of Physiology, EarlyView.Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski +3 more
wiley +1 more source
Effects of Medications on the in vitro Growth of Gut Bacteria Associated With Kidney Stones
Kidney International ReportsJing Bi Karchin +4 more
doaj +1 more source
MFS-transporter Flr1 is a major drug-efflux transporter in Saccharomyces cerevisiae ascospores. [PDF]
FEMS Yeast ResAdamovich AM, Knorre DA, Galkina KV.
europepmc +1 more source
Physiological and anatomical determinants of placental drug transfer
The Journal of Physiology, EarlyView.Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis +3 more
wiley +1 more source
The Pyruvate-Glyoxalate Pathway as a Toxicity Assessment Tool of Xenobiotics: Lessons from Prebiotic Chemistry. [PDF]
J XenobiotGagné F, André C.
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida +7 more
wiley +1 more source
Exposure to pesticides in drinking water during pregnancy and risk of congenital malformations: a systematic review protocol. [PDF]
BMJ OpenRiboni C +3 more
europepmc +1 more source