Results 241 to 250 of about 77,053 (291)

Nephrotoxicity of xenobiotics

Clinica Chimica Acta, 1995
Nephrotoxicity can be grouped by the xenobiotics place of action, by the clinical presentation or by the generic toxic effect. The latter can be dose related, indirect, idiosyncratic or allergic. Nephrotoxicity of lithium, demeclocycline, aminoglycosides, cyclosporine, mercuric ion, nonsteroidal anti-inflammatory drugs, methoxyflurane, ethylene glycol,
M, Werner, M J, Costa, L G, Mitchell, R, Nayar   +3 more
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Xenobiotic and Non-Xenobiotic Interventions in the Microbiome Therapeutics

Current Drug Metabolism, 2015
It is now very much clear that the microbiome plays an important part in human health. Microbiome is associated with several diseases and targeting the whole microbiome is certainly a challenge before the scientists. The "Human Microbiome Project" is continually exploring certain therapeutic targets inside microbiome landscape that could be utilized ...
Vipin, Kumar, Pradeep, Kumar, Vikas, Sharma   +2 more
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Interactions Among Infections, Nutrients and Xenobiotics

Critical Reviews in Food Science and Nutrition, 2007
During recent years there have been several incidents in which symptoms of disease have been linked to consumption of food contaminated by chemical substances (e.g., 2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD). Furthermore, outbreaks of infections in food-
Göran Friman, Nils-Gunnar Ilbäck
exaly   +2 more sources

Biliary Excretion of Xenobiotics

CRC Critical Reviews in Toxicology, 1975
The biliary route is very important for the elimination of some foreign compounds from the body. For many of these compounds, an increase in the rate at which they are excreted into the bile will decrease their toxicity and vice versa. A number of factors which are known to alter the biliary excretion of xenobiotics, as well as the current concepts of ...
Curtis D. Klaassen, Gabriel L. Plaa
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The Effects of Xenobiotics on Erythrocytes

General Pharmacology: The Vascular System, 1998
1. Methemoglobin formation was observed when erythrocytes were incubated with xenobiotics such as hydroxylamines or phenols, other metabolites resulting from the interaction of these compounds with erythrocytes being reactive free radicals derived from the respective xenobiotic, and a ferryl-heme oxo-complex. 2.
H, Nohl, K, Stolze
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Xenobiotic metabolism in helminths

Parasitology Today, 1989
During its life cycle a parasite, like mammals and other organisms, comes into contact with a variety of toxic molecules. In mammals the main line of defence against such compounds is a group of oxidative enzymes that occur predominantly in the liver. Many of these oxidations are dependent on the haemoprotein cytochrome P-450 which serves as a terminal
W Y, Precious, J, Barrett
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Co-oxidation of xenobiotics

Biochemical Society Transactions, 1985
Co-oxidation of xenobiotics has been shown t o occur during prostaglandin synthase (PGS)-catalysed synthesis of prostaglandins (Marnett. 198 I ; EIing et al.. 1983; Marnett & Eling. 1983). PGS catalyses the oxygenation of polyunsaturated fatty acids to hydroxy endoperoxides (e.g. PGH2).
P, Moldéus, D, Ross, R, Larsson
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Intestinal responses to xenobiotics

Toxicology in Vitro, 2001
The gastrointestinal tract represents the first barrier met by the exogenous compounds of food or orally delivered drugs. To be transferred to the whole body, drugs and xenobiotics have first to pass through the intestinal epithelium, where detoxification systems have to minimize the potential of damage from toxic xenobiotics.
V, Carrière, J, Chambaz, M, Rousset
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Xenobiotic Metabolism in Brain

Drug Metabolism Reviews, 1995
(1995). Xenobiotic Metabolism in Brain. Drug Metabolism Reviews: Vol. 27, No. 3, pp. 419-448.
V, Ravindranath, M R, Boyd
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Inhibition of Sulfotransferases by Xenobiotics

Current Drug Metabolism, 2006
The sulfotransferase (SULT) family comprises important phase II conjugation enzymes for the detoxification of xenobiotics and modulation of the activity of physiologically important endobiotics such as thyroid hormones, steroids, and neurotransmitters.
Li-Quan, Wang, Margaret O, James
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