Xenodiagnosis to address key questions in visceral leishmaniasis control and elimination. [PDF]
PLoS Neglected Tropical Diseases, 2020 Visceral leishmaniasis (VL) remains an important public health issue worldwide causing substantial morbidity and mortality. The Indian subcontinent accounted for up to 90% of the global VL burden in the past but made significant progress during recent ...
Om Prakash Singh +4 more
doaj +6 more sources
Parasite persistence in treated chagasic patients revealed by xenodiagnosis and polymerase chain reaction [PDF]
Memorias do Instituto Oswaldo Cruz, 2001 Polymerase chain reaction (PCR) was compared with xenodiagnosis performed 20 years after trypanocidal chemotherapy to investigate parasite clearance. Eighty-five seropositive individuals for Chagas disease presenting a positive xenodiagnosis were treated
Constança Britto +6 more
doaj +7 more sources
Leishmania infantum xenodiagnosis from vertically infected dogs reveals significant skin tropism. [PDF]
PLoS Negl Trop Dis, 2021 Background Dogs are the primary reservoir for human visceral leishmaniasis due to Leishmania infantum. Phlebotomine sand flies maintain zoonotic transmission of parasites between dogs and humans. A subset of dogs is infected transplacentally during gestation, but at what stage of the clinical spectrum vertically infected dogs contribute to the ...
Scorza BM +12 more
europepmc +9 more sources
Xenodiagnosis in the wild: A methodology to investigate infectiousness for tick-borne bacteria in a songbird reservoir. [PDF]
Curr Res Parasitol Vector Borne DisA crucial factor to predict the persistence and spread of infections in natural systems is the capacity of reservoir hosts to maintain the infection and transmit it to others. This is known to greatly vary within and between species and through time, although the latter part of the variation is often less well understood in the wild.
Zarka J +5 more
europepmc +8 more sources
Discrete Typing Units of Trypanosoma cruzi Identified by Real-Time PCR in Peripheral Blood and Dejections of Triatoma infestans Used in Xenodiagnosis Descriptive Study [PDF]
Pathogens, 2022 Chagas disease (ChD) is a vector zoonosis native to the American continent caused by the protozoan parasite Trypanosoma cruzi; the biological vectors are multiple species of hematophagous insects of the family Triatominae.
Inés Zulantay +8 more
doaj +4 more sources
Experimental evaluation of xenodiagnosis to detect trypanosomes at low parasitaemia levels in infected hosts [PDF]
Parasite, 2011 In Human African Trypanosomosis (HAT) endemic areas, there are a number of subjects that are positive to serological tests but in whom trypanosomes are difficult to detect with the available parasitological tests.
Wombou Toukam C.M. +4 more
doaj +6 more sources
Infectiousness of Asymptomatic Meriones shawi, Reservoir Host of Leishmania major [PDF]
Pathogens, 2023 Leishmaniases are neglected diseases caused by protozoans of the genus Leishmania that threaten millions of people worldwide. Cutaneous leishmaniasis (CL) caused by L.
Jovana Sadlova +8 more
doaj +2 more sources
The Role of the Leishmania infantum Infected Dogs as a Potential Reservoir Host for Toscana Virus in a Zoonotic Visceral Leishmaniasis Focus of Northern Tunisia [PDF]
Viruses, 2023 The role of dogs as reservoir hosts for Toscana virus (TOSV) remains undetermined. This study investigated TOSV and Leishmania infantum infections in one healthy and three infected dogs with Leishmania (A, B, C) following natural exposition to sandfly ...
Khalil Dachraoui +9 more
doaj +2 more sources
Infectiousness to sand flies of a cat naturally infected with Leishmania infantum at the moment of diagnosis and after three different courses of treatment [PDF]
Revista Brasileira de Parasitologia VeterináriaIn this study, an evaluation was made of three treatments against feline leishmaniosis (FeL) and their impacts on the transmission of Leishmania infantum to its vector, Lutzomyia longipalpis. A cat with clinical signs of FeL was examined and L.
Mariana Dantas da Silva +8 more
doaj +2 more sources
Examining the Relationship of Clinical and Laboratory Parameters With Infectiousness to Phlebotomus perniciosus and Its Potential Infectivity in Dogs With Overt Clinical Leishmaniasis [PDF]
Frontiers in Veterinary Science, 2021 Infected dogs are considered the main domestic animal reservoirs for Leishmania infantum parasite. Infectiousness to competent phlebotomine vectors has been associated with many factors, the main being the severity of the disease exhibited by infected ...
Manuela Gizzarelli +13 more
doaj +2 more sources