Xenodiagnosis to address key questions in visceral leishmaniasis control and elimination. [PDF]
PLoS Neglected Tropical Diseases, 2020 Visceral leishmaniasis (VL) remains an important public health issue worldwide causing substantial morbidity and mortality. The Indian subcontinent accounted for up to 90% of the global VL burden in the past but made significant progress during recent ...
Om Prakash Singh +4 more
doaj +6 more sources
Discrete Typing Units of Trypanosoma cruzi Identified by Real-Time PCR in Peripheral Blood and Dejections of Triatoma infestans Used in Xenodiagnosis Descriptive Study [PDF]
Pathogens, 2022 Chagas disease (ChD) is a vector zoonosis native to the American continent caused by the protozoan parasite Trypanosoma cruzi; the biological vectors are multiple species of hematophagous insects of the family Triatominae.
Inés Zulantay +8 more
doaj +3 more sources
Leishmania infantum xenodiagnosis from vertically infected dogs reveals significant skin tropism. [PDF]
PLoS Negl Trop Dis, 2021 Background Dogs are the primary reservoir for human visceral leishmaniasis due to Leishmania infantum. Phlebotomine sand flies maintain zoonotic transmission of parasites between dogs and humans.
Scorza BM +12 more
europepmc +8 more sources
Xenodiagnosis in the wild: A methodology to investigate infectiousness for tick-borne bacteria in a songbird reservoir. [PDF]
Curr Res Parasitol Vector Borne DisA crucial factor to predict the persistence and spread of infections in natural systems is the capacity of reservoir hosts to maintain the infection and transmit it to others. This is known to greatly vary within and between species and through time, although the latter part of the variation is often less well understood in the wild.
Zarka J +5 more
europepmc +8 more sources
Parasite persistence in treated chagasic patients revealed by xenodiagnosis and polymerase chain reaction [PDF]
Memorias do Instituto Oswaldo Cruz, 2001 Polymerase chain reaction (PCR) was compared with xenodiagnosis performed 20 years after trypanocidal chemotherapy to investigate parasite clearance. Eighty-five seropositive individuals for Chagas disease presenting a positive xenodiagnosis were treated
Constança Britto +6 more
doaj +6 more sources
Experimental evaluation of xenodiagnosis to detect trypanosomes at low parasitaemia levels in infected hosts [PDF]
Parasite, 2011 In Human African Trypanosomosis (HAT) endemic areas, there are a number of subjects that are positive to serological tests but in whom trypanosomes are difficult to detect with the available parasitological tests.
Wombou Toukam C.M. +4 more
doaj +6 more sources
Xenodiagnosis of Leishmania donovani in BALB/c mice using Phlebotomus orientalis: a new laboratory model [PDF]
Parasites & Vectors, 2015 Background In areas endemic for visceral leishmaniasis (VL), the majority of infected hosts remain asymptomatic but potentially infectious to biting sand flies.
Jovana Sadlova +4 more
doaj +5 more sources
Laboratory evidence that dinotefuran, pyriproxyfen and permethrin combination abrogates Leishmania infantum transmissibility by sick dogs. [PDF]
Med Vet Entomol, 2022 The effect of dinotefuran, pyriproxyfen and permethrin spot‐on solution (Vectra®3D) on Leishmania infantum transmissibility by naturally sick dogs via reared Phlebotomus perniciosus, was assessed. Six dogs submitted to xenodiagnosis and infecting >10% of sand fly females were treated on day 0; anti‐transmissibility effects were evaluated again by ...
Bongiorno G +13 more
europepmc +2 more sources
FML/QuilA-Vaccinated Dogs Naturally Infected with Leishmania infantum: Serum Cytokines, Clinicopathological Profile, and Parasitological Parameters. [PDF]
Biomed Res Int, 2021 Dogs are the main reservoir of Leishmania infantum in endemic regions. Canine leishmaniasis, caused by L. infantum, can progress to a chronic disease resulting in death. Vaccines have been developed with a certain degree of success. The pathogenesis of this disease is not completely understood, especially in previously vaccinated dogs.
Almeida GG +5 more
europepmc +2 more sources
Infectiousness of Asymptomatic Meriones shawi, Reservoir Host of Leishmania major [PDF]
Pathogens, 2023 Leishmaniases are neglected diseases caused by protozoans of the genus Leishmania that threaten millions of people worldwide. Cutaneous leishmaniasis (CL) caused by L.
Jovana Sadlova +8 more
doaj +2 more sources