Results 21 to 30 of about 2,998 (210)

Xenodiagnosis to Detect Borrelia burgdorferi Infection: A First-in-Human Study [PDF]

Clinical Infectious Diseases, 2014
Animal studies suggest that Borrelia burgdorferi, the agent of Lyme disease, may persist after antibiotic therapy and can be detected by various means including xenodiagnosis using the natural tick vector (Ixodes scapularis). No convincing evidence exists for the persistence of viable spirochetes after recommended courses of antibiotic therapy in ...
Christina Brandeburg, Pamela A. Shaw, Chris D. Crowder, Linden T. Hu, Carla Williams, Siu-Ping Turk, Erin Chung, Sam R. Telford, Mark W. Eshoo, Heather E. Carolan, Peter J. Krause, Adriana Marques, Kenneth R. Dardick   +12 more
openaire   +3 more sources

Editorial Commentary: Xenodiagnosis for Posttreatment Lyme Disease Syndrome: Resolving the Conundrum or Adding to It? [PDF]

Clinical Infectious Diseases, 2014
(See the Major Article by Marques et al on pages 937–45.) The first reports of Lyme disease in Connecticut in the mid-1970s, followed by the discovery of its tick-borne etiologic agent, Borrelia burgdorferi, in 1983, has spawned one of the longest controversies in the history of biomedical research [1].
Linda K. Bockenstedt, Justin D. Radolf
openaire   +3 more sources

Light effect on feeding of first instar Dipetalogaster maximus in xenodiagnosis [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 1993
over a period of ten years suggest that a smaller quantity of blood is being ingested by hungry first instar bugs1 3. Since in Mexico the majority of bugs are first instar of diumal habit it was suggested that feeding might be related to light intensity2.
Menezes, M.N.A., Garcia-Zapata, M.T.A., Castro, C.N., Soares, V.A., Marsden, P.D.   +4 more
  +10 more sources

Absence of both circadian rhythm and Trypanosoma cruzi periodicity with xenodiagnosis in chronic chagasic individuals Ausência de ritmo circadiano e de periodicidade do Trypanosoma cruzi ao xenodiagnóstico em chagásicos crônicos [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2000
Xenodiagnoses were performed every 3 hours using 10 Triatoma infestans 3rd instar for 24 to 72 hours, in 18 chronic chagasics with positive serology and/or xenodiagnosis.
Cleudson Castro, Aluizio Prata
doaj   +2 more sources

Chronic Chagas disease: PCR-xenodiagnosis without previous microscopic observation is a useful tool to detect viable Trypanosoma cruzi [PDF]

Biological Research, 2013
We evaluate the elimination of the microscopic stage of conventional xenodiagnosis (XD) to optimize the parasitological diagnosis of Trypanosoma cruzi in chronic Chagas disease.
Miguel Saavedra, Inés Zulantay, Werner Apt, Gabriela Martínez, Antonio Rojas, Jorge Rodríguez   +5 more
doaj   +2 more sources

Quantifying the Infectiousness of Post-Kala-Azar Dermal Leishmaniasis Toward Sand Flies. [PDF]

Clin Infect Dis, 2019
Background In the Indian subcontinent, visceral leishmaniasis (VL) incidence is on track to reach elimination goals by 2020 in nearly all endemic districts.
Mondal D, Bern C, Ghosh D, Rashid M, Molina R, Chowdhury R, Nath R, Ghosh P, Chapman LAC, Alim A, Bilbe G, Alvar J.   +11 more
europepmc   +4 more sources

Heterogeneities in leishmania infantum infection : using skin parasite burdens to identify highly infectious dogs [PDF]

, 2013
Background: The relationships between heterogeneities in host infection and infectiousness (transmission to arthropod vectors) can provide important insights for disease management.
A Mohammadiha, A Mohammadiha, ANS Maia-Elkhoury, AP da Costa-Val, AP Galvani, BL Travi, BLA Vercosa, C Carson, C Fraser, C Mary, C Mary, CDL Oliveira, CHN Costa, CHN Costa, Connor Carson, DJ Shaw, DW Dowdy, EM Michalsky, GA Soper, IFGd Amorim, JO Lloyd-Smith, KJ Esch, KTD Eames, L Dipineto, L Manna, L Manna, L Matthews, Leo Calvo-Bado, LHdS Marques, LLH Lau, Lourdes M. Garcez, LVR Lima, M Chase-Topping, Marleen Boelaert, MEJ Woolhouse, O Courtenay, O Courtenay, O Courtenay, O Francino, Orin Courtenay, PF Quaresma, R Lainson, R Molina, R Molina, R Verin, RA Stein, RB Gomes, RC Giunchetti, RJ Quinnell, RJ Quinnell, RJ Quinnell, RJ Quinnell, RM Anderson, RM May, Rupert J. Quinnell, S Bossolasco, SdA Ferreira   +56 more
core   +27 more sources

Real-Time PCR in faecal samples of Triatoma infestans obtained by xenodiagnosis: proposal for an exogenous internal control [PDF]

Parasites & Vectors, 2012
Abstract Background The polymerase chain reaction (PCR) has proved to be a sensitive technique to detect Trypanosoma cruzi in the chronic phase of Chagas disease, which is characterized by low and fluctuating parasitemia.
Bravo, Nicolás, Mũoz, Catalina, Nazal, Nicolás, Saavedra, Miguel, Martínez, Gabriela, Acha Araya, Eduardo Javier, Apt Baruch, Werner, Zulantay Alfaro, Inés   +7 more
openaire   +11 more sources

Laboratory evidence that dinotefuran, pyriproxyfen and permethrin combination abrogates Leishmania infantum transmissibility by sick dogs. [PDF]

Med Vet Entomol, 2022
The effect of dinotefuran, pyriproxyfen and permethrin spot‐on solution (Vectra®3D) on Leishmania infantum transmissibility by naturally sick dogs via reared Phlebotomus perniciosus, was assessed. Six dogs submitted to xenodiagnosis and infecting >10% of sand fly females were treated on day 0; anti‐transmissibility effects were evaluated again by ...
Bongiorno G, Bosco A, Bianchi R, Rinaldi L, Foglia Manzillo V, Gizzarelli M, Maurelli MP, Giaquinto D, El Houda Ben Fayala N, Varloud M, Crippa A, Oliva G, Gradoni L, Cringoli G.   +13 more
europepmc   +2 more sources

FML/QuilA-Vaccinated Dogs Naturally Infected with Leishmania infantum: Serum Cytokines, Clinicopathological Profile, and Parasitological Parameters. [PDF]

Biomed Res Int, 2021
Dogs are the main reservoir of Leishmania infantum in endemic regions. Canine leishmaniasis, caused by L. infantum, can progress to a chronic disease resulting in death. Vaccines have been developed with a certain degree of success. The pathogenesis of this disease is not completely understood, especially in previously vaccinated dogs.
Almeida GG, Coura FM, de Melo Barbieri J, Moura ACJ, de Oliveira Paes-Leme F, da Costa-Val AP.   +5 more
europepmc   +2 more sources