Results 61 to 70 of about 3,068 (220)

A case–control study on risk factors for visceral leishmaniasis in West Pokot County, Kenya

Tropical Medicine &International Health, Volume 29, Issue 10, Page 904-912, October 2024.
Abstract Background Visceral leishmaniasis (VL) is a severe parasitic disease transmitted by phlebotomine sandflies. VL is endemic in West Pokot County, Kenya, where effective strategies to interrupt transmission are impeded by the limited understanding of VL risk factors.
Norbert J. van Dijk, Jane Carter, David Kiptanui, Petra F. Mens, Henk D. F. H. Schallig   +4 more
wiley   +1 more source

Revisiting the Posttherapeutic Cure Criterion in Chagas Disease: Time for New Methods, More Questions, Doubts, and Polemics or Time to Change Old Concepts?

BioMed Research International, Volume 2015, Issue 1, 2015., 2015
One of the most relevant issues beyond the effectiveness of etiological treatment of Chagas disease is the lack of consensual/feasible tools to identify and certify the definitive parasitological cure. Several methods of distinct natures (parasitological, serological, and molecular) have been continuously proposed and novel perspectives are currently ...
Marta de Lana, Olindo Assis Martins-Filho, David Bruce Conn   +2 more
wiley   +1 more source

Physiological Age Structure and Leishmania spp. Detection in Phlebotomus (Larroussius) orientalis (Parrot, 1936) (Diptera: Psychodidae) at an Endemic Focus of Visceral Leishmaniasis in Northern Ethiopia

Journal of Tropical Medicine, Volume 2015, Issue 1, 2015., 2015
Visceral leishmaniasis (VL) caused by Leishmania donovani is endemic in northern Ethiopia, where P. orientalis is the most important presumed vector. This study was designed to determine the physiological age structure and the occurrence of Leishmania infection in the vector of VL in Tahtay Adiyabo district, northern Ethiopia. Sand flies were collected
Araya Gebresilassie, Ibrahim Abbasi, Oscar David Kirstein, Essayas Aklilu, Solomon Yared, Habte Tekie, Meshesha Balkew, Alon Warburg, Asrat Hailu, Teshome Gebre-Michael, Shyam Sundar   +10 more
wiley   +1 more source

CD8+ T Cell‐Mediated Immunity during Trypanosoma cruzi Infection: A Path for Vaccine Development?

Mediators of Inflammation, Volume 2014, Issue 1, 2014., 2014
MHC‐restricted CD8+ T cells are important during infection with the intracellular protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease. Experimental studies performed in the past 25 years have elucidated a number of features related to the immune response mediated by these T cells, which are important for establishing the ...
Fernando dos Santos Virgilio, Camila Pontes, Mariana Ribeiro Dominguez, Jonatan Ersching, Mauricio Martins Rodrigues, José Ronnie Vasconcelos, Edecio Cunha-Neto   +6 more
wiley   +1 more source

Within-host temporal fluctuations of Trypanosoma cruzi discrete typing units: the case of the wild reservoir rodent Octodon degus

Parasites & Vectors, 2017
Background Chagas disease caused by Trypanosoma cruzi is considered a major public health problem in America. After an acute phase the disease changes to a chronic phase with very low parasitemia. The parasite presents high genetic variability with seven
Gemma Rojo, Alejandra Sandoval-Rodríguez, Angélica López, Sylvia Ortiz, Juana P. Correa, Miguel Saavedra, Carezza Botto-Mahan, Pedro E. Cattan, Aldo Solari   +8 more
doaj   +1 more source

Infectiousness in a Cohort of Brazilian Dogs: Why Culling Fails to Control Visceral Leishmaniasis in Areas of High Transmission [PDF]

, 2002
The elimination of seropositive dogs in Brazil has been used to control zoonotic visceral leishmaniasis but with little success. To elucidate the reasons for this, the infectiousness of 50 sentinel dogs exposed to natural Leishmania chagasi infection was
Courtenay, O., Dye, C., Garcez, L.M., Quinnell, R.J., Shaw, J.J.   +4 more
core  

Combining epidemiology with basic biology of sand flies, parasites, and hosts to inform leishmaniasis transmission dynamics and control. [PDF]

, 2017
Quantitation of the nonlinear heterogeneities in Leishmania parasites, sand fly vectors, and mammalian host relationships provides insights to better understand leishmanial transmission epidemiology towards improving its control. The parasite manipulates
Bern, Caryn, Courtenay, Orin, Peters, Nathan C, Rogers, Matthew E   +3 more
core   +3 more sources

Chagas’ Disease: Pregnancy and Congenital Transmission

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
Chagas disease is a chronic infection that kills approximately 12,000 people a year. Mass migration of chronically infected and asymptomatic persons has caused globalization of Chagas disease and has made nonvectorial infection, including vertical and blood‐borne transmission, more of a threat to human communities than vectorial infection.
Ana María Cevallos, Roberto Hernández, Veeranoot Nissapatorn   +2 more
wiley   +1 more source

Insights on adaptive and innate immunity in canine leishmaniosis [PDF]

, 2016
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a systemic disease, which can present with variable clinical signs, and clinicopathological abnormalities.
Abi Abdallah, Alexander, Catchpole, DAMER P. BLAKE, de Souza Carmo, Green, Kensil, LAIA SOLANO-GALLEGO, Lopez, Margarito, Ordeix, Pinelli, Pitta, Quinnell, Sadick, Sanchez, SHAZIA HOSEIN, Silva, Vouldoukis, Wakelin   +19 more
core   +4 more sources

Additional data on the epidemiology of chagas disease in the municipality of Caxias, Rio de Janeiro state, Brazil

Revista da Sociedade Brasileira de Medicina Tropical, 1975
An area believed to be an autochthonous focus for Chagas' disease was investigated in the municipality of Caxias, Rio de Janeiro State. The study included search for domestic triatomine bugs, serological test (IFT and CFT) in persons in whose house ...
J. Rodrigues Coura, Walter B. Petana
doaj   +3 more sources